Serum feline trypsin-like immunoreactivity following administration of ceruletide to healthy cats

Thomas Spillmann, Inès Jacob, Jörg M. Steiner, David A. Williams, Klaus Failing

Research output: Contribution to journalArticle

Abstract

Objective - To determine changes in serum feline trypsin-like immunoreactivity (fTLI) in response to administration of ceruletide to healthy cats. Animals - 11 healthy cats. Procedures - Serum fTLI was determined, using a radioimmunoassay, before and 10, 20, 30, 40, and 50 minutes after IM administration of ceruletide (0.3 mg/kg [0.14 mg/lb]). Results - Mean ± SD baseline serum fTLl was 23.1 ± 4.1 mg/L. There was a statistically significant, but clinically unimportant, increase in serum fTLi 10 and 30 minutes after ceruletide administration. Conclusions and Clinical Relevance - In healthy cats, administration of ceruletide induced a statistically significant, but clinically unimportant, increase in serum fTLl. Whether responses in cats with exocrine pancreatic disorders would be different is unknown, but results suggest that a ceruletide stimulation test would likely not be useful for differentiating between healthy cats and cats with subclinical chronic exocrine pancreatic disorders.

Original languageEnglish (US)
Pages (from-to)925-927
Number of pages3
JournalAmerican journal of veterinary research
Volume61
Issue number8
DOIs
StatePublished - Aug 2000
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)

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