SERS aptasensor from nanorod-nanoparticle junction for protein detection

Yuling Wang, Kyuwan Lee, Joseph Irudayaraj

Research output: Contribution to journalArticle

Abstract

A multicomponent nanostructure comprising of gold nanorod-nanoparticle (AuNR-AuNP) composites was fabricated to detect thrombin at subnanomolar concentrations in diluted human blood serum. Simulation and experiments revealed that the strong electromagnetic coupling resonance at the nanorod-nanoparticle junction of these probes can be used to construct highly sensitive SERS aptasensors.

Original languageEnglish (US)
Pages (from-to)613-615
Number of pages3
JournalChemical Communications
Volume46
Issue number4
DOIs
StatePublished - Feb 1 2010
Externally publishedYes

Fingerprint

Nanorods
Nanoparticles
Proteins
Electromagnetic coupling
Thrombin
Gold
Nanostructures
Blood
Composite materials
Experiments

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

SERS aptasensor from nanorod-nanoparticle junction for protein detection. / Wang, Yuling; Lee, Kyuwan; Irudayaraj, Joseph.

In: Chemical Communications, Vol. 46, No. 4, 01.02.2010, p. 613-615.

Research output: Contribution to journalArticle

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