Semiconductor Quantum Dots for Multicolor Fluorescence Imaging and Spectroscopy of Single Cancer Cells

Xiaohu Gao, Shinning Nie

Research output: Contribution to journalConference articlepeer-review

Abstract

Luminescent quantum dots (QDs) are emerging as a new class of biological labels with unique properties and applications that are not available from traditional organic dyes and fluorescent proteins. Here we report new developments in using semiconductor quantum dots for quantitative imaging and spectroscopy of single cancer cells. We show that both live and fixed cells can be labeled with multicolor QDs, and that single cells can be analyzed by fluorescence imaging and wavelength-resolved spectroscopy. These results raise new possibilities in cancer imaging, molecular profiling, and disease staging.

Original languageEnglish (US)
Pages (from-to)69-76
Number of pages8
JournalMaterials Research Society Symposium - Proceedings
Volume773
DOIs
StatePublished - Jan 1 2003
Externally publishedYes
EventBiomicroelectromechanical Systems (BioMEMS) - San Francisco, CA, United States
Duration: Apr 22 2003Apr 25 2003

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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