Segmenting Alzheimer's Disease MRI Slices for Hippocampal Volume Calculation

Hsiao Chuan Tan, Gilang Titah Ramadhan, Wei Cheng Shen, Wen Thong Chang, Chih Yang Lin, Ben Yi Liau, Yih Kuen Jan, Yori Pusparani, Chi Wen Lung

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Alzheimer's is a neurodegenerative disease that quietly steals human memory. This study analyzed hippocampal volume in Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI), and Normal Cognition (NC) using MRI image slices from the ADNI database and YOLOv8 instance segmentation. We used 300 images to segment the left and right hippocampal. This study focused on volume calculation from five MRI image slices. The results showed 0.98 (AD), 0.92 (MCI), and 0.90 (NC) and revealed significant volumetric differences showed in the NC class (P = 0.045). This suggests early neuroanatomical changes can occur without cognitive symptoms, highlighting the potential of deep learning in the early detection of neurodegenerative diseases.

Original languageEnglish (US)
Title of host publication11th IEEE International Conference on Consumer Electronics - Taiwan, ICCE-Taiwan 2024
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages307-308
Number of pages2
ISBN (Electronic)9798350386844
DOIs
StatePublished - 2024
Event11th IEEE International Conference on Consumer Electronics - Taiwan, ICCE-Taiwan 2024 - Taichung, Taiwan, Province of China
Duration: Jul 9 2024Jul 11 2024

Publication series

Name11th IEEE International Conference on Consumer Electronics - Taiwan, ICCE-Taiwan 2024

Conference

Conference11th IEEE International Conference on Consumer Electronics - Taiwan, ICCE-Taiwan 2024
Country/TerritoryTaiwan, Province of China
CityTaichung
Period7/9/247/11/24

Keywords

  • Brain
  • Neuroanatomy
  • Volume
  • YOLO

ASJC Scopus subject areas

  • Human-Computer Interaction
  • Electrical and Electronic Engineering
  • Media Technology
  • Modeling and Simulation
  • Instrumentation

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