SeaBase: A multispecies transcriptomic resource and platform for gene network inference

Antje H.L. Fischer, Dmitry Mozzherin, A. Murat Eren, Kristen D. Lans, Nathan Wilson, Carlo Cosentino, Joel Smith

Research output: Contribution to journalArticlepeer-review


Marine and aquatic animals are extraordinarily useful as models for identifying mechanisms of development and evolution, regeneration, resistance to cancer, longevity and symbiosis, among many other areas of research. This is due to the great diversity of these organisms and their wide-ranging capabilities. Genomics tools are essential for taking advantage of these free lessons of nature. However, genomics and transcriptomics are challenging in emerging model systems. Here, we present SeaBase, a tool for helping to meet these needs. Specifically, SeaBase provides a platform for sharing and searching transcriptome data. More importantly, SeaBase will support a growing number of tools for inferring gene network mechanisms. The first dataset available on SeaBase is a developmental transcriptomic profile of the sea anemone Nematostella vectensis (Anthozoa, Cnidaria). Additional datasets are currently being prepared and we are aiming to expand SeaBase to include user-supplied data for any number of marine and aquatic organisms, thereby supporting many potentially new models for gene network studies. SeaBase can be accessed online at:

Original languageEnglish (US)
Pages (from-to)250-263
Number of pages14
JournalIntegrative and comparative biology
Issue number2
StatePublished - Jul 2014
Externally publishedYes

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Plant Science


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