A series of model compounds has been labeled with bromine-77 using a recently described method for rapid radiobromination. Characterization of the 77Br-labeled products has shown the technique to be unsuitable for labeling fragile molecules, such as proteins. Thus, the technique should not be considered a generally applicable radiobromination method; however, it may be a useful means of attaching radiobromine to some simple molecules which are not sensitive to oxidative conditions and do not possess multiple sites for halogenation.
ASJC Scopus subject areas
- Nuclear Energy and Engineering
- Radiology Nuclear Medicine and imaging