Scaffolding protein IQGAP1 is dispensable, but its overexpression promotes hepatocellular carcinoma via YAP1 signaling

Keyphrases

• Overexpression 100%
• Scaffold Protein 100%
• Hepatocellular Carcinoma 100%
• IQ-domain GTPase-activating Protein 1 100%
• YAP1 Signaling 100%
• Liver Carcinogenesis 30%
• Liver 20%
• Cell Proliferation 20%
• Beta-catenin 20%
• YAP Activation 20%
• Cell Adhesion 10%
• Cell Motility 10%
• Tumor Cells 10%
• Clinically Significant 10%
• Tumorigenesis 10%
• Tumor Burden 10%
• Pro-tumorigenic 10%
• Tumor Promotion 10%
• Multiple Signaling Pathways 10%
• Liver Cancer 10%
• Ectopic Overexpression 10%
• Rapid Onset 10%
• Carcinogenesis Models 10%
• Diethylnitrosamine 10%
• Tumor Initiation 10%
• Hepatocellular Carcinoma Progression 10%
• MET Signaling 10%
• Antitumor Target 10%
• NUAK2 10%

Biochemistry, Genetics and Molecular Biology

• Synapsin I 100%
• Scaffold Protein 100%
• GTPase-activating Protein 100%
• YAP1 100%
• Carcinogenesis 40%
• Cell Proliferation 20%
• Catenin 20%
• Signal Transduction 10%
• Cell Adhesion 10%
• Mouse 10%
• Cell Motility 10%
• Tumor Volume 10%
• Tumor Initiation 10%

Medicine and Dentistry

• Hepatocellular Carcinoma 100%
• Scaffold Protein 100%
• Liver Carcinogenesis 30%
• Cell Proliferation 20%
• Catenin 20%
• Neoplasm 10%
• Malignant Neoplasm 10%
• Carcinogenesis 10%
• Signal Transduction 10%
• Cell Adhesion 10%
• Cell Motility 10%
• Liver Cancer 10%
• Tumor Initiation 10%
• Tumor Promotion 10%
• Diethylnitrosamine 10%