Saccharomyces cerevisiae α-factor prevents formation of glycoproteins in a cells

Peter Orlean, Gabi Seebacher, Widmar Tanner

Research output: Contribution to journalArticlepeer-review

Abstract

α-Factor inhibits incorporation of [14C]glucosamine into water-soluble and into SDS-extractable glycoproteins to about 90%. The incorporation into chitin is not affected and the same is true for [14C]phenylalanine incorporation into protein. The inhibition of glycoprotein synthesis is specific for a cells.

Original languageEnglish (US)
Pages (from-to)247-251
Number of pages5
JournalFEBS Letters
Volume158
Issue number2
DOIs
StatePublished - Jul 25 1983
Externally publishedYes

Keywords

  • Cell cycle
  • G1 arrest
  • Glycoprotein
  • Yeast
  • α-Factor

ASJC Scopus subject areas

  • Biophysics
  • Structural Biology
  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology

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