Roles for LBP and soluble CD14 in cellular uptake of LPS.

R. I. Tapping; J. A. Gegner; V. V. Kravchenko; P. S. Tobias

Roles for LBP and soluble CD14 in cellular uptake of LPS.

R. I. Tapping, J. A. Gegner, V. V. Kravchenko, P. S. Tobias

Research output: Contribution to journal › Review article › peer-review

Abstract

Roles for LBP and CD14 in the LPS dependent activation of a wide variety of cells have been established. In the work described here, we describe roles for these proteins in the binding and uptake of LPS by cells which express membrane CD14 and those which do not. Surprisingly, cell activation and LPS uptake appear to be independent phenomena with different protein requirements.

Original language	English (US)
Pages (from-to)	73-78
Number of pages	6
Journal	Progress in clinical and biological research
Volume	397
State	Published - 1998

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Medicine(all)

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title = "Roles for LBP and soluble CD14 in cellular uptake of LPS.",

abstract = "Roles for LBP and CD14 in the LPS dependent activation of a wide variety of cells have been established. In the work described here, we describe roles for these proteins in the binding and uptake of LPS by cells which express membrane CD14 and those which do not. Surprisingly, cell activation and LPS uptake appear to be independent phenomena with different protein requirements.",

author = "Tapping, {R. I.} and Gegner, {J. A.} and Kravchenko, {V. V.} and Tobias, {P. S.}",

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AU - Tapping, R. I.

AU - Gegner, J. A.

AU - Kravchenko, V. V.

AU - Tobias, P. S.

PY - 1998

Y1 - 1998

N2 - Roles for LBP and CD14 in the LPS dependent activation of a wide variety of cells have been established. In the work described here, we describe roles for these proteins in the binding and uptake of LPS by cells which express membrane CD14 and those which do not. Surprisingly, cell activation and LPS uptake appear to be independent phenomena with different protein requirements.

AB - Roles for LBP and CD14 in the LPS dependent activation of a wide variety of cells have been established. In the work described here, we describe roles for these proteins in the binding and uptake of LPS by cells which express membrane CD14 and those which do not. Surprisingly, cell activation and LPS uptake appear to be independent phenomena with different protein requirements.

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M3 - Review article

C2 - 9575548

AN - SCOPUS:0031638699

SN - 0361-7742

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SP - 73

EP - 78

JO - Progress in Clinical and Biological Research

JF - Progress in Clinical and Biological Research

ER -

Roles for LBP and soluble CD14 in cellular uptake of LPS.

Abstract

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