Role of the lymphatics in cancer metastasis and chemotherapy applications

Jennifer D. McAllaster; Mark S. Cohen

doi:10.1016/j.addr.2011.05.014

Role of the lymphatics in cancer metastasis and chemotherapy applications

Jennifer D. McAllaster, Mark S. Cohen

Research output: Contribution to journal › Review article › peer-review

Abstract

The lymphatic system was first described centuries ago. The recent discovery of various molecular markers has allowed for more in-depth research of the lymphatic system and its role in health and disease. The lymphatic system has recently been elucidated as playing an active role in cancer metastasis. The knowledge of the active processes involved in lymphatic metastasis provides novel treatment targets for various malignancies.

Original language	English (US)
Pages (from-to)	867-875
Number of pages	9
Journal	Advanced Drug Delivery Reviews
Volume	63
Issue number	10-11
DOIs	https://doi.org/10.1016/j.addr.2011.05.014
State	Published - Sep 10 2011
Externally published	Yes

Keywords

Lymphangiogenesis
Lymphatic anatomy
Lymphatic endothelial cells
Lymphatic metastasis
Lymphatic vasculature
Vascular endothelial growth factors

ASJC Scopus subject areas

Pharmaceutical Science

Online availability

10.1016/j.addr.2011.05.014

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title = "Role of the lymphatics in cancer metastasis and chemotherapy applications",

abstract = "The lymphatic system was first described centuries ago. The recent discovery of various molecular markers has allowed for more in-depth research of the lymphatic system and its role in health and disease. The lymphatic system has recently been elucidated as playing an active role in cancer metastasis. The knowledge of the active processes involved in lymphatic metastasis provides novel treatment targets for various malignancies.",

keywords = "Lymphangiogenesis, Lymphatic anatomy, Lymphatic endothelial cells, Lymphatic metastasis, Lymphatic vasculature, Vascular endothelial growth factors",

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AU - Cohen, Mark S.

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AB - The lymphatic system was first described centuries ago. The recent discovery of various molecular markers has allowed for more in-depth research of the lymphatic system and its role in health and disease. The lymphatic system has recently been elucidated as playing an active role in cancer metastasis. The knowledge of the active processes involved in lymphatic metastasis provides novel treatment targets for various malignancies.

KW - Lymphangiogenesis

KW - Lymphatic anatomy

KW - Lymphatic endothelial cells

KW - Lymphatic metastasis

KW - Lymphatic vasculature

KW - Vascular endothelial growth factors

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ER -

Role of the lymphatics in cancer metastasis and chemotherapy applications

Abstract

Keywords

ASJC Scopus subject areas

Online availability

Library availability

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