Role of methionine in bacterial chemotaxis: Requirement for tumbling and involvement in information processing

M. S. Springer, E. N. Kort, S. H. Larsen, G. W. Ordal, R. W. Reader, J. Adler

Research output: Contribution to journalArticlepeer-review

Abstract

Chemotactic responses are mediated by nodulation of the frequency of tumbling. Studies with methionine auxotrophs of wild type E. coli and four mutants which tumble continuously show that methionine or one of its metabolites is involved in the tumbling process. Following removal of methionine, the wild type and two mutants, after various periods of time, became unable to tumble. The presence of constant levels of chemical attractants considerably shortened these periods in the three strains and eliminated tumbling in another mutant. This effect of attractants implies that methionine or some derivative of methionine is also involved in transducing chemical stimuli to bacterial responses.

Original languageEnglish (US)
Pages (from-to)4640-4644
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume72
Issue number11
DOIs
StatePublished - 1975
Externally publishedYes

ASJC Scopus subject areas

  • General

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