Role of lysosomes in cellular lytic processes. I. Effect of carbon starvation in Euglena gracilis

David Brandes; D. E. Buetow; Francesco Bertini; D. B. Malkoff

doi:10.1016/0014-4800(64)90036-X

Role of lysosomes in cellular lytic processes. I. Effect of carbon starvation in Euglena gracilis

David Brandes, D. E. Buetow, Francesco Bertini, D. B. Malkoff

Research output: Contribution to journal › Article › peer-review

Abstract

The fine structure and the ultrastructural localization of acid phosphatase have been investigated in normally grown and in carbon-starved Euglena gracilis of a streptomycin-bleached strain. During starvation, portions of the cytoplasm, including mitochondria, become encapsulated within membrane-bound cavities comparable to cytolysomes and autophagic vacuoles described in mammalian cells. Progressive degradation of the encapsulated material may represent a mechanism for providing the cell with breakdown products for utilization in continued maintenance of basic metabolic processes. Strong evidence is presented on the participation of the Golgi apparatus both in the formation of the cytolysomes and as the source of the acid phosphatase found within these bodies.

Original language	English (US)
Pages (from-to)	583-609
Number of pages	27
Journal	Experimental and Molecular Pathology
Volume	3
Issue number	6
DOIs	https://doi.org/10.1016/0014-4800(64)90036-X
State	Published - Dec 1964
Externally published	Yes

ASJC Scopus subject areas

Pathology and Forensic Medicine
Molecular Biology
Clinical Biochemistry

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10.1016/0014-4800(64)90036-X

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title = "Role of lysosomes in cellular lytic processes. I. Effect of carbon starvation in Euglena gracilis",

abstract = "The fine structure and the ultrastructural localization of acid phosphatase have been investigated in normally grown and in carbon-starved Euglena gracilis of a streptomycin-bleached strain. During starvation, portions of the cytoplasm, including mitochondria, become encapsulated within membrane-bound cavities comparable to cytolysomes and autophagic vacuoles described in mammalian cells. Progressive degradation of the encapsulated material may represent a mechanism for providing the cell with breakdown products for utilization in continued maintenance of basic metabolic processes. Strong evidence is presented on the participation of the Golgi apparatus both in the formation of the cytolysomes and as the source of the acid phosphatase found within these bodies.",

author = "David Brandes and Buetow, {D. E.} and Francesco Bertini and Malkoff, {D. B.}",

note = "Funding Information: 1 This investigation was supported by grants and Human Development, and CA-OS424 from of Health, U.S. Public Health Service. z Present address: Department of Neurology, Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",

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language = "English (US)",

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AU - Brandes, David

AU - Buetow, D. E.

AU - Bertini, Francesco

AU - Malkoff, D. B.

N1 - Funding Information: 1 This investigation was supported by grants and Human Development, and CA-OS424 from of Health, U.S. Public Health Service. z Present address: Department of Neurology, Copyright: Copyright 2018 Elsevier B.V., All rights reserved.

PY - 1964/12

Y1 - 1964/12

N2 - The fine structure and the ultrastructural localization of acid phosphatase have been investigated in normally grown and in carbon-starved Euglena gracilis of a streptomycin-bleached strain. During starvation, portions of the cytoplasm, including mitochondria, become encapsulated within membrane-bound cavities comparable to cytolysomes and autophagic vacuoles described in mammalian cells. Progressive degradation of the encapsulated material may represent a mechanism for providing the cell with breakdown products for utilization in continued maintenance of basic metabolic processes. Strong evidence is presented on the participation of the Golgi apparatus both in the formation of the cytolysomes and as the source of the acid phosphatase found within these bodies.

AB - The fine structure and the ultrastructural localization of acid phosphatase have been investigated in normally grown and in carbon-starved Euglena gracilis of a streptomycin-bleached strain. During starvation, portions of the cytoplasm, including mitochondria, become encapsulated within membrane-bound cavities comparable to cytolysomes and autophagic vacuoles described in mammalian cells. Progressive degradation of the encapsulated material may represent a mechanism for providing the cell with breakdown products for utilization in continued maintenance of basic metabolic processes. Strong evidence is presented on the participation of the Golgi apparatus both in the formation of the cytolysomes and as the source of the acid phosphatase found within these bodies.

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Role of lysosomes in cellular lytic processes. I. Effect of carbon starvation in Euglena gracilis

Abstract

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