Role of lysosomes in cellular lytic processes. I. Effect of carbon starvation in Euglena gracilis

David Brandes, D. E. Buetow, Francesco Bertini, D. B. Malkoff

Research output: Contribution to journalArticle

Abstract

The fine structure and the ultrastructural localization of acid phosphatase have been investigated in normally grown and in carbon-starved Euglena gracilis of a streptomycin-bleached strain. During starvation, portions of the cytoplasm, including mitochondria, become encapsulated within membrane-bound cavities comparable to cytolysomes and autophagic vacuoles described in mammalian cells. Progressive degradation of the encapsulated material may represent a mechanism for providing the cell with breakdown products for utilization in continued maintenance of basic metabolic processes. Strong evidence is presented on the participation of the Golgi apparatus both in the formation of the cytolysomes and as the source of the acid phosphatase found within these bodies.

Original languageEnglish (US)
Pages (from-to)583-609
Number of pages27
JournalExperimental and Molecular Pathology
Volume3
Issue number6
DOIs
StatePublished - Dec 1964

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ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Molecular Biology
  • Clinical Biochemistry

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