Role of Electrostatics in Protein-RNA Binding: The Global vs the Local Energy Landscape

Keyphrases

• Binding Site 100%
• Energy Landscape 100%
• Protein-RNA Binding 100%
• Local Energy 100%
• Electrostatic Interaction 75%
• Long-range Electrostatics 50%
• Short-range Interaction 50%
• Stem-loop 50%
• Specific Binding 50%
• Binding Landscape 50%
• Molecular Dynamics Simulation 25%
• Hydrogen Bonds (H-bonds) 25%
• Negatively Charged 25%
• Kinetic Behavior 25%
• Bound States 25%
• Binding Affinity 25%
• Novel Functions 25%
• Positive Charge 25%
• Temperature Jump 25%
• Tryptophan 25%
• RNA-protein Complex 25%
• Computational Prediction 25%
• RNA-binding Domain 25%
• RNA-protein Interaction 25%
• Local Minima 25%
• Aromatic Residues 25%
• Experimental Temperature 25%
• Multiple Binding Sites 25%
• Site Function 25%
• Local Contact 25%
• Jump Kinetics 25%
• Protein Side Chains 25%
• U1 Small nuclear Ribonucleoprotein 25%
• RNA-protein Binding 25%
• Hydrogen Contacts 25%

Biochemistry, Genetics and Molecular Biology

• RNA 100%
• Binding Site 100%
• Static Electricity 100%
• Energy Landscape 100%
• RNA-binding Protein 100%
• Stem-Loop 33%
• Dynamics 16%
• Hydrogen Bond 16%
• Binding Affinity 16%
• Tryptophan 16%
• RNA Binding 16%
• SnRNP 16%