Road condition is an important environmental factor for autonomous vehicle control. A dramatic change in the road condition from the nominal status is a source of uncertainty that can lead to a system failure. Once the vehicle encounters an uncertain environment, such as hitting an ice patch, it is too late to reduce the speed, and the vehicle can lose control. To cope with unforeseen uncertainties in advance, we study a proactive robust adaptive control architecture for autonomous vehicles' lane-keeping control problems. The data center generates a prior environmental uncertainty estimate by combining weather forecasts and measurements from anonymous vehicles through a spatio-temporal filter. The prior estimate contributes to designing a robust heading controller and nominal longitudinal velocity for proactive adaptation to each new condition. The control parameters are updated based on posterior information fusion with on-board measurements.