RNA World

Research output: Chapter in Book/Report/Conference proceedingChapter


The RNA world hypotheses explain the emergence of modern biochemistry and the origin of life by postulating the existence of a primordial molecular world with self-replicating and catalytic molecules made of RNA. The initial role of these molecules was later extended in evolution from metabolism and replication to translation and transcription.

Original languageEnglish (US)
Title of host publicationBrenner's Encyclopedia of Genetics
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Number of pages3
ISBN (Electronic)9780080961569
ISBN (Print)9780123749840
StatePublished - Feb 27 2013


  • Evolution
  • In vitro evolution
  • Non-ribosomal protein synthesis
  • Origin of life
  • Peptidyl transferase center
  • Phylogenomics
  • Prebiotic chemistry
  • Protein
  • RNA
  • Ribonuclease P
  • Ribosomal RNA
  • Ribosome
  • Ribozyme
  • Self-replication
  • Transfer RNA

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology
  • General Medicine


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