Abstract
The present invention relates to a new class of novel Rhodamine derivatives. These derivatives which are bisamide substitution products are nonfluorescent. Whereas the monoamide substitution products exhibit high fluorescence. Cleavage of a single specified amide bond by bond-specific proteinases will therefore convert the nonfluorescent bisamide derivative into a highly fluorescent monoamide derivative.
| Original language | English (US) |
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| U.S. patent number | 4557862 |
| Filing date | 10/28/83 |
| State | Published - Dec 10 1985 |