Research Progress on the Role of M6A in Regulating Economic Traits in Livestock

Tuanhui Ren; Meng Xu; Xinyu Du; Yanxi Wang; Juan J. Loor; Lin Lei; Wenwen Gao; Xiliang Du; Yuxiang Song; Guowen Liu; Xinwei Li

doi:10.3390/ijms25158365

Research Progress on the Role of M6A in Regulating Economic Traits in Livestock

Tuanhui Ren, Meng Xu, Xinyu Du, Yanxi Wang, Juan J. Loor, Lin Lei, Wenwen Gao, Xiliang Du, Yuxiang Song, Guowen Liu, Xinwei Li

Research output: Contribution to journal › Review article › peer-review

Abstract

Reversible regulation of N6-methyladenosine (m6A) methylation of eukaryotic RNA via methyltransferases is an important epigenetic event affecting RNA metabolism. As such, m6A methylation plays crucial roles in regulating animal growth, development, reproduction, and disease progression. Herein, we review the latest research advancements in m6A methylation modifications and discuss regulatory aspects in the context of growth, development, and reproductive traits of livestock. New insights are highlighted and perspectives for the study of m6A methylation modifications in shaping economically important traits are discussed.

Original language	English (US)
Article number	8365
Journal	International journal of molecular sciences
Volume	25
Issue number	15
DOIs	https://doi.org/10.3390/ijms25158365
State	Published - Aug 2024

Keywords

m6A methylation
reproductive traits
growth and development
livestock
methyltransferases

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10.3390/ijms25158365License: CC BY

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title = "Research Progress on the Role of M6A in Regulating Economic Traits in Livestock",

abstract = "Reversible regulation of N6-methyladenosine (m6A) methylation of eukaryotic RNA via methyltransferases is an important epigenetic event affecting RNA metabolism. As such, m6A methylation plays crucial roles in regulating animal growth, development, reproduction, and disease progression. Herein, we review the latest research advancements in m6A methylation modifications and discuss regulatory aspects in the context of growth, development, and reproductive traits of livestock. New insights are highlighted and perspectives for the study of m6A methylation modifications in shaping economically important traits are discussed.",

keywords = "m6A methylation, reproductive traits, growth and development, livestock, methyltransferases",

author = "Tuanhui Ren and Meng Xu and Xinyu Du and Yanxi Wang and Loor, {Juan J.} and Lin Lei and Wenwen Gao and Xiliang Du and Yuxiang Song and Guowen Liu and Xinwei Li",

note = "This research was funded by the Jilin Province Young and Middle-aged Outstanding Talent in Science and Technology Innovation and Entrepreneurship (20230508020RC) and the Fundamental Research Funds for the Central Universities (2022-JCXK-21).",

year = "2024",

month = aug,

doi = "10.3390/ijms25158365",

language = "English (US)",

volume = "25",

journal = "International journal of molecular sciences",

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T1 - Research Progress on the Role of M6A in Regulating Economic Traits in Livestock

AU - Ren, Tuanhui

AU - Xu, Meng

AU - Du, Xinyu

AU - Wang, Yanxi

AU - Loor, Juan J.

AU - Lei, Lin

AU - Gao, Wenwen

AU - Du, Xiliang

AU - Song, Yuxiang

AU - Liu, Guowen

AU - Li, Xinwei

N1 - This research was funded by the Jilin Province Young and Middle-aged Outstanding Talent in Science and Technology Innovation and Entrepreneurship (20230508020RC) and the Fundamental Research Funds for the Central Universities (2022-JCXK-21).

PY - 2024/8

Y1 - 2024/8

N2 - Reversible regulation of N6-methyladenosine (m6A) methylation of eukaryotic RNA via methyltransferases is an important epigenetic event affecting RNA metabolism. As such, m6A methylation plays crucial roles in regulating animal growth, development, reproduction, and disease progression. Herein, we review the latest research advancements in m6A methylation modifications and discuss regulatory aspects in the context of growth, development, and reproductive traits of livestock. New insights are highlighted and perspectives for the study of m6A methylation modifications in shaping economically important traits are discussed.

AB - Reversible regulation of N6-methyladenosine (m6A) methylation of eukaryotic RNA via methyltransferases is an important epigenetic event affecting RNA metabolism. As such, m6A methylation plays crucial roles in regulating animal growth, development, reproduction, and disease progression. Herein, we review the latest research advancements in m6A methylation modifications and discuss regulatory aspects in the context of growth, development, and reproductive traits of livestock. New insights are highlighted and perspectives for the study of m6A methylation modifications in shaping economically important traits are discussed.

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KW - reproductive traits

KW - growth and development

KW - livestock

KW - methyltransferases

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U2 - 10.3390/ijms25158365

DO - 10.3390/ijms25158365

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ER -

Research Progress on the Role of M6A in Regulating Economic Traits in Livestock

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