Research highlights from the Purdue-UAB Botanicals Research Center for Age Related Diseases

Connie M. Weaver; Stephen Barnes; J. Michael Wyss; Helen Kim; Dorothy M. Morré; D. James Morré; James E. Simon; Mary Ann Lila; Elsa M. Janle; Mario G. Ferruzzi

doi:10.1080/13880200902988603

Research highlights from the Purdue-UAB Botanicals Research Center for Age Related Diseases

Connie M. Weaver, Stephen Barnes, J. Michael Wyss, Helen Kim, Dorothy M. Morré, D. James Morré, James E. Simon, Mary Ann Lila, Elsa M. Janle, Mario G. Ferruzzi

Natural Resources and Environmental Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

The Purdue-UAB Botanicals Research Center for Age Related Disease uses multidisciplinary and innovative technologies to investigate the bioavailability of bioactive polyphenolic constituents from botanicals and their relationship to human health. Many age-related diseases are associated with oxidative stress and tissue damage. One of the research goals of the Purdue-UAB Center is to investigate the bioavailability of bioactive natural compounds from a complex botanical mixture to the organ affected by the disease, determine the uptake and metabolism of these compounds, and relate these data to a protective mechanism. Equally important is to screen commercially available botanicals for their safety and efficacy. The central aims of the Center include the investigation of botanicals and their relationship to bone antiresorptive capacity, cognitive function, vascular effects, and cancer prevention.

Original language	English (US)
Pages (from-to)	768-773
Number of pages	6
Journal	Pharmaceutical Biology
Volume	47
Issue number	8
DOIs	https://doi.org/10.1080/13880200902988603
State	Published - Aug 2009

Keywords

Bone resorption
Botanicals
Cancer
Catechins
Cognitive function
Isoflavones

ASJC Scopus subject areas

Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine

Online availability

10.1080/13880200902988603

Library availability

Discover UIUC Full Text

Cite this

@article{e548f5526a224264a25ef234da59e002,

title = "Research highlights from the Purdue-UAB Botanicals Research Center for Age Related Diseases",

abstract = "The Purdue-UAB Botanicals Research Center for Age Related Disease uses multidisciplinary and innovative technologies to investigate the bioavailability of bioactive polyphenolic constituents from botanicals and their relationship to human health. Many age-related diseases are associated with oxidative stress and tissue damage. One of the research goals of the Purdue-UAB Center is to investigate the bioavailability of bioactive natural compounds from a complex botanical mixture to the organ affected by the disease, determine the uptake and metabolism of these compounds, and relate these data to a protective mechanism. Equally important is to screen commercially available botanicals for their safety and efficacy. The central aims of the Center include the investigation of botanicals and their relationship to bone antiresorptive capacity, cognitive function, vascular effects, and cancer prevention.",

keywords = "Bone resorption, Botanicals, Cancer, Catechins, Cognitive function, Isoflavones",

author = "Weaver, {Connie M.} and Stephen Barnes and Wyss, {J. Michael} and Helen Kim and Morr{\'e}, {Dorothy M.} and Morr{\'e}, {D. James} and Simon, {James E.} and Lila, {Mary Ann} and Janle, {Elsa M.} and Ferruzzi, {Mario G.}",

note = "Funding Information: Declaration of interest: This research was supported by Office of Dietary Supplements and NCCAM Grant P50 AT 00477. One of the authors (C.M.W.) is on the advisory boards of Pharmavite and Wyeth. She receives grant support from Wyeth, and reviews research proposals for the United Soybean Board. None of the other authors identified an affiliation.",

year = "2009",

month = aug,

doi = "10.1080/13880200902988603",

language = "English (US)",

volume = "47",

pages = "768--773",

journal = "Pharmaceutical Biology",

issn = "1388-0209",

publisher = "Informa Healthcare",

number = "8",

}

TY - JOUR

T1 - Research highlights from the Purdue-UAB Botanicals Research Center for Age Related Diseases

AU - Weaver, Connie M.

AU - Barnes, Stephen

AU - Wyss, J. Michael

AU - Kim, Helen

AU - Morré, Dorothy M.

AU - Morré, D. James

AU - Simon, James E.

AU - Lila, Mary Ann

AU - Janle, Elsa M.

AU - Ferruzzi, Mario G.

N1 - Funding Information: Declaration of interest: This research was supported by Office of Dietary Supplements and NCCAM Grant P50 AT 00477. One of the authors (C.M.W.) is on the advisory boards of Pharmavite and Wyeth. She receives grant support from Wyeth, and reviews research proposals for the United Soybean Board. None of the other authors identified an affiliation.

PY - 2009/8

Y1 - 2009/8

N2 - The Purdue-UAB Botanicals Research Center for Age Related Disease uses multidisciplinary and innovative technologies to investigate the bioavailability of bioactive polyphenolic constituents from botanicals and their relationship to human health. Many age-related diseases are associated with oxidative stress and tissue damage. One of the research goals of the Purdue-UAB Center is to investigate the bioavailability of bioactive natural compounds from a complex botanical mixture to the organ affected by the disease, determine the uptake and metabolism of these compounds, and relate these data to a protective mechanism. Equally important is to screen commercially available botanicals for their safety and efficacy. The central aims of the Center include the investigation of botanicals and their relationship to bone antiresorptive capacity, cognitive function, vascular effects, and cancer prevention.

AB - The Purdue-UAB Botanicals Research Center for Age Related Disease uses multidisciplinary and innovative technologies to investigate the bioavailability of bioactive polyphenolic constituents from botanicals and their relationship to human health. Many age-related diseases are associated with oxidative stress and tissue damage. One of the research goals of the Purdue-UAB Center is to investigate the bioavailability of bioactive natural compounds from a complex botanical mixture to the organ affected by the disease, determine the uptake and metabolism of these compounds, and relate these data to a protective mechanism. Equally important is to screen commercially available botanicals for their safety and efficacy. The central aims of the Center include the investigation of botanicals and their relationship to bone antiresorptive capacity, cognitive function, vascular effects, and cancer prevention.

KW - Bone resorption

KW - Botanicals

KW - Cancer

KW - Catechins

KW - Cognitive function

KW - Isoflavones

UR - http://www.scopus.com/inward/record.url?scp=77149154393&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77149154393&partnerID=8YFLogxK

U2 - 10.1080/13880200902988603

DO - 10.1080/13880200902988603

M3 - Article

AN - SCOPUS:77149154393

SN - 1388-0209

VL - 47

SP - 768

EP - 773

JO - Pharmaceutical Biology

JF - Pharmaceutical Biology

IS - 8

ER -

Research highlights from the Purdue-UAB Botanicals Research Center for Age Related Diseases

Abstract

Keywords

ASJC Scopus subject areas

Online availability

Library availability

Related links

Fingerprint

Cite this