Research findings from nonpharmaceutical intervention studies for pandemic influenza and current gaps in the research

Allison E. Aiello, Rebecca M. Coulborn, Tomas J. Aragon, Michael G. Baker, Barri B. Burrus, Benjamin J. Cowling, Alasdair Duncan, Wayne Enanoria, M. Patricia Fabian, Yu hui Ferng, Elaine L. Larson, Gabriel M. Leung, Howard Markel, Donald K. Milton, Arnold S. Monto, Stephen S. Morse, J. Alexander Navarro, Sarah Y. Park, Patricia Priest, Samuel StebbinsAlexandra M. Stern, Monica Uddin, Scott F. Wetterhall, Charles J. Vukotich

Research output: Contribution to journalArticle

Abstract

In June 2006, the Centers for Disease Control and Prevention released a request for applications to identify, improve, and evaluate the effectiveness of nonpharmaceutical interventions (NPIs)-strategies other than vaccines and antiviral medications-to mitigate the spread of pandemic influenza within communities and across international borders (RFA-CI06-010). These studies have provided major contributions to seasonal and pandemic influenza knowledge. Nonetheless, key concerns were identified related to the acceptability and protective efficacy of NPIs. Large-scale intervention studies conducted over multiple influenza epidemics, as well as smaller studies in controlled laboratory settings, are needed to address the gaps in the research on transmission and mitigation of influenza in the community setting. The current novel influenza A (H1N1) pandemic underscores the importance of influenza research.

Original languageEnglish (US)
Pages (from-to)251-258
Number of pages8
JournalAmerican Journal of Infection Control
Volume38
Issue number4
DOIs
StatePublished - May 2010

Keywords

  • Hand hygiene
  • infection control
  • masks
  • transmission

ASJC Scopus subject areas

  • Epidemiology
  • Health Policy
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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  • Cite this

    Aiello, A. E., Coulborn, R. M., Aragon, T. J., Baker, M. G., Burrus, B. B., Cowling, B. J., Duncan, A., Enanoria, W., Fabian, M. P., Ferng, Y. H., Larson, E. L., Leung, G. M., Markel, H., Milton, D. K., Monto, A. S., Morse, S. S., Navarro, J. A., Park, S. Y., Priest, P., ... Vukotich, C. J. (2010). Research findings from nonpharmaceutical intervention studies for pandemic influenza and current gaps in the research. American Journal of Infection Control, 38(4), 251-258. https://doi.org/10.1016/j.ajic.2009.12.007