Reproductive performance and three-dimensional ultrasound volume determination of polycystic ovaries following laparoscopic ovarian drilling

Togos Tulandi, Kenneth Watkin, Seang Lin Tan

Research output: Contribution to journalArticlepeer-review

Abstract

Objective - To evaluate the changes in ovarian volume and the reproductive outcome after laparoscopic treatment of polycystic ovaries (PCOS) in clomiphene-resistant anovulatory women. Design - A prospective study of women undergoing laparoscopic treatment of polycystic ovaries. Ultrasound examination for three-dimensional (3D) volume determination was performed before and after surgery. Setting -University teaching hospital. Patients - Thirty-four women with polycystic ovarian syndrome who failed to ovulate with clomiphene citrate and who subsequently underwent laparoscopic ovarian drilling. Interventions - Laparoscopic ovarian drilling and three- dimensional ultrasound examination. Main Outcome Measures - Cumulative probability of conception and changes in ovarian volume. Results - Ovulation rate after the procedure was 30/34 (88.2%). Using Life Table Analysis, the cumulative probability of conception at 12 months follow-up was 70% (median, 8.1 months). The preoperative ovarian volume was 12.2 ± 1.8 cm3 and 1 week after surgery it was 13.6 ± 1.5 cm3. The ovarian volume 3 weeks after surgery, 6.9 ± 1.3 cm3, was significantly smaller than that before surgery. Conclusions - Laparoscopic treatment of polycystic ovaries in women with clomiphene-resistant PCOS is associated with an ovulation rate of 88.2% and a cumulative pregnancy rate of 70% at 12 months. It appears also that laparoscopic ovarian drilling may result in a transient increase, with a subsequent significant reduction, in ovarian volume.

Original languageEnglish (US)
Pages (from-to)436-440
Number of pages5
JournalInternational Journal of Fertility and Women's Medicine
Volume42
Issue number6
StatePublished - Jan 1 1997

Keywords

  • Laparoscopy
  • Polycystic ovarian syndrome
  • Pregnancy
  • Ultrasound

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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