Renewed debate over postnatal oogenesis in the mammalian ovary

Chuck Greenfeld, Jodi A. Flaws

Research output: Contribution to journalReview article

Abstract

The central dogma of female reproductive biology has long held that oogenesis ceases prior to birth in mammals. During the first half of the last century, there was much debate about whether this was the case or whether oogenesis continued in the postnatal ovary. A report in 1951 effectively put an end to this debate and laid the foundation for the dogma. A new paper by Johnson et al. (2004) resurrects the debate over whether postnatal oogenesis occurs in the mammalian ovary. If confirmed, this would have tremendous impact on issues related to female fertility and reproductive longevity.

Original languageEnglish (US)
Pages (from-to)829-832
Number of pages4
JournalBioEssays
Volume26
Issue number8
DOIs
StatePublished - Aug 2004

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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