Reliability of gait in multiple sclerosis over 6 months

Jacob J. Sosnoff, Rachel E. Klaren, Lara A. Pilutti, Deirdre Dlugonski, Robert W. Motl

Research output: Contribution to journalArticle

Abstract

Gait impairment is ubiquitous in multiple sclerosis (MS) and is often characterized by alterations in spatiotemporal parameters of gait. There is limited information concerning reliability of spatiotemporal gait parameters over clinical timescales (e.g. 6 months). The current report provides novel evidence that gait parameters of 74 ambulatory persons with MS with mild-to-moderate disability are reliable over 6-months (ICC's for overall sample range from 0.56 to 0.91) in the absence of any intervention above and beyond standard care. Such data can inform clinical decision-making and power analyses for designing RCTs (i.e., sample size estimates) involving persons with MS.

Original languageEnglish (US)
Pages (from-to)860-862
Number of pages3
JournalGait and Posture
Volume41
Issue number3
DOIs
StatePublished - Mar 1 2015

Keywords

  • Gait
  • Locomotion
  • Multiple sclerosis
  • Reliability
  • Sample size estimates

ASJC Scopus subject areas

  • Biophysics
  • Orthopedics and Sports Medicine
  • Rehabilitation

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  • Cite this

    Sosnoff, J. J., Klaren, R. E., Pilutti, L. A., Dlugonski, D., & Motl, R. W. (2015). Reliability of gait in multiple sclerosis over 6 months. Gait and Posture, 41(3), 860-862. https://doi.org/10.1016/j.gaitpost.2015.02.006