Relationships between gastrointestinal parasite infections and the fecal microbiome in free-ranging western lowland gorillas

Klára Vlčková, Barbora Pafčo, Klára J. Petrželková, David Modrý, Angelique Todd, Carl J. Yeoman, Manolito Torralba, Brenda Anne Wilson, Rebecca Stumpf, Bryan A. White, Karen E. Nelson, Steven R. Leigh, Andres Gomez

Research output: Contribution to journalArticle

Abstract

Relationships between gastrointestinal parasites (GIPs) and the gastrointestinal microbiome (GIM) are widely discussed topics across mammalian species due to their possible impact on the host's health. GIPs may change the environment determining alterations in GIM composition. We evaluated the associations between GIP infections and fecal microbiome composition in two habituated and two unhabituated groups of wild western lowland gorillas (Gorilla g. gorilla) from Dzanga Sangha Protected Areas, Central African Republic. We examined 43 fecal samples for GIPs and quantified strongylid nematodes. We characterized fecal microbiome composition through 454 pyrosequencing of the V1-V3 region of the bacterial 16S rRNA gene. Entamoeba spp. infections were associated with significant differences in abundances of bacterial taxa that likely play important roles in nutrition and metabolism for the host, besides being characteristic members of the gorilla gut microbiome. We did not observe any relationships between relative abundances of several bacterial taxa and strongylid egg counts. Based on our findings, we suggest that there is a significant relationship between fecal microbiome and Entamoeba infection in wild gorillas. This study contributes to the overall knowledge about factors involved in modulating GIM communities in great apes.

Original languageEnglish (US)
Article number1202
JournalFrontiers in Microbiology
Volume9
Issue numberJUN
DOIs
StatePublished - Jun 15 2018

Fingerprint

Gorilla gorilla
Parasitic Diseases
Microbiota
Entamoeba
Parasites
Central African Republic
Hominidae
Infection
rRNA Genes
Ovum
Gastrointestinal Microbiome
Health

Keywords

  • Bacteria
  • Entamoeba
  • Fecal microbiome
  • Lowland gorilla
  • Parasite infection
  • Strongylid nematodes

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Vlčková, K., Pafčo, B., Petrželková, K. J., Modrý, D., Todd, A., Yeoman, C. J., ... Gomez, A. (2018). Relationships between gastrointestinal parasite infections and the fecal microbiome in free-ranging western lowland gorillas. Frontiers in Microbiology, 9(JUN), [1202]. https://doi.org/10.3389/fmicb.2018.01202

Relationships between gastrointestinal parasite infections and the fecal microbiome in free-ranging western lowland gorillas. / Vlčková, Klára; Pafčo, Barbora; Petrželková, Klára J.; Modrý, David; Todd, Angelique; Yeoman, Carl J.; Torralba, Manolito; Wilson, Brenda Anne; Stumpf, Rebecca; White, Bryan A.; Nelson, Karen E.; Leigh, Steven R.; Gomez, Andres.

In: Frontiers in Microbiology, Vol. 9, No. JUN, 1202, 15.06.2018.

Research output: Contribution to journalArticle

Vlčková, K, Pafčo, B, Petrželková, KJ, Modrý, D, Todd, A, Yeoman, CJ, Torralba, M, Wilson, BA, Stumpf, R, White, BA, Nelson, KE, Leigh, SR & Gomez, A 2018, 'Relationships between gastrointestinal parasite infections and the fecal microbiome in free-ranging western lowland gorillas', Frontiers in Microbiology, vol. 9, no. JUN, 1202. https://doi.org/10.3389/fmicb.2018.01202
Vlčková, Klára ; Pafčo, Barbora ; Petrželková, Klára J. ; Modrý, David ; Todd, Angelique ; Yeoman, Carl J. ; Torralba, Manolito ; Wilson, Brenda Anne ; Stumpf, Rebecca ; White, Bryan A. ; Nelson, Karen E. ; Leigh, Steven R. ; Gomez, Andres. / Relationships between gastrointestinal parasite infections and the fecal microbiome in free-ranging western lowland gorillas. In: Frontiers in Microbiology. 2018 ; Vol. 9, No. JUN.
@article{cf1d92ff7161474cacdc42da3049c532,
title = "Relationships between gastrointestinal parasite infections and the fecal microbiome in free-ranging western lowland gorillas",
abstract = "Relationships between gastrointestinal parasites (GIPs) and the gastrointestinal microbiome (GIM) are widely discussed topics across mammalian species due to their possible impact on the host's health. GIPs may change the environment determining alterations in GIM composition. We evaluated the associations between GIP infections and fecal microbiome composition in two habituated and two unhabituated groups of wild western lowland gorillas (Gorilla g. gorilla) from Dzanga Sangha Protected Areas, Central African Republic. We examined 43 fecal samples for GIPs and quantified strongylid nematodes. We characterized fecal microbiome composition through 454 pyrosequencing of the V1-V3 region of the bacterial 16S rRNA gene. Entamoeba spp. infections were associated with significant differences in abundances of bacterial taxa that likely play important roles in nutrition and metabolism for the host, besides being characteristic members of the gorilla gut microbiome. We did not observe any relationships between relative abundances of several bacterial taxa and strongylid egg counts. Based on our findings, we suggest that there is a significant relationship between fecal microbiome and Entamoeba infection in wild gorillas. This study contributes to the overall knowledge about factors involved in modulating GIM communities in great apes.",
keywords = "Bacteria, Entamoeba, Fecal microbiome, Lowland gorilla, Parasite infection, Strongylid nematodes",
author = "Kl{\'a}ra Vlčkov{\'a} and Barbora Pafčo and Petrželkov{\'a}, {Kl{\'a}ra J.} and David Modr{\'y} and Angelique Todd and Yeoman, {Carl J.} and Manolito Torralba and Wilson, {Brenda Anne} and Rebecca Stumpf and White, {Bryan A.} and Nelson, {Karen E.} and Leigh, {Steven R.} and Andres Gomez",
year = "2018",
month = "6",
day = "15",
doi = "10.3389/fmicb.2018.01202",
language = "English (US)",
volume = "9",
journal = "Frontiers in Microbiology",
issn = "1664-302X",
publisher = "Frontiers Media S. A.",
number = "JUN",

}

TY - JOUR

T1 - Relationships between gastrointestinal parasite infections and the fecal microbiome in free-ranging western lowland gorillas

AU - Vlčková, Klára

AU - Pafčo, Barbora

AU - Petrželková, Klára J.

AU - Modrý, David

AU - Todd, Angelique

AU - Yeoman, Carl J.

AU - Torralba, Manolito

AU - Wilson, Brenda Anne

AU - Stumpf, Rebecca

AU - White, Bryan A.

AU - Nelson, Karen E.

AU - Leigh, Steven R.

AU - Gomez, Andres

PY - 2018/6/15

Y1 - 2018/6/15

N2 - Relationships between gastrointestinal parasites (GIPs) and the gastrointestinal microbiome (GIM) are widely discussed topics across mammalian species due to their possible impact on the host's health. GIPs may change the environment determining alterations in GIM composition. We evaluated the associations between GIP infections and fecal microbiome composition in two habituated and two unhabituated groups of wild western lowland gorillas (Gorilla g. gorilla) from Dzanga Sangha Protected Areas, Central African Republic. We examined 43 fecal samples for GIPs and quantified strongylid nematodes. We characterized fecal microbiome composition through 454 pyrosequencing of the V1-V3 region of the bacterial 16S rRNA gene. Entamoeba spp. infections were associated with significant differences in abundances of bacterial taxa that likely play important roles in nutrition and metabolism for the host, besides being characteristic members of the gorilla gut microbiome. We did not observe any relationships between relative abundances of several bacterial taxa and strongylid egg counts. Based on our findings, we suggest that there is a significant relationship between fecal microbiome and Entamoeba infection in wild gorillas. This study contributes to the overall knowledge about factors involved in modulating GIM communities in great apes.

AB - Relationships between gastrointestinal parasites (GIPs) and the gastrointestinal microbiome (GIM) are widely discussed topics across mammalian species due to their possible impact on the host's health. GIPs may change the environment determining alterations in GIM composition. We evaluated the associations between GIP infections and fecal microbiome composition in two habituated and two unhabituated groups of wild western lowland gorillas (Gorilla g. gorilla) from Dzanga Sangha Protected Areas, Central African Republic. We examined 43 fecal samples for GIPs and quantified strongylid nematodes. We characterized fecal microbiome composition through 454 pyrosequencing of the V1-V3 region of the bacterial 16S rRNA gene. Entamoeba spp. infections were associated with significant differences in abundances of bacterial taxa that likely play important roles in nutrition and metabolism for the host, besides being characteristic members of the gorilla gut microbiome. We did not observe any relationships between relative abundances of several bacterial taxa and strongylid egg counts. Based on our findings, we suggest that there is a significant relationship between fecal microbiome and Entamoeba infection in wild gorillas. This study contributes to the overall knowledge about factors involved in modulating GIM communities in great apes.

KW - Bacteria

KW - Entamoeba

KW - Fecal microbiome

KW - Lowland gorilla

KW - Parasite infection

KW - Strongylid nematodes

UR - http://www.scopus.com/inward/record.url?scp=85048592882&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85048592882&partnerID=8YFLogxK

U2 - 10.3389/fmicb.2018.01202

DO - 10.3389/fmicb.2018.01202

M3 - Article

VL - 9

JO - Frontiers in Microbiology

JF - Frontiers in Microbiology

SN - 1664-302X

IS - JUN

M1 - 1202

ER -