Rel-(1R,6S,7S,8R,9S)-9-methyl-8-phenyl-6-[(1S,2R)-(2-phenylcyclohexyl)oxy]- 4-aza-3,5-dioxatricyclo[5.2.1.04,9]decane

Julie A. Dixon; Kevin A. Swiss; Scott E. Denmark

doi:10.1107/S0108270196006671

Rel-(1R,6S,7S,8R,9S)-9-methyl-8-phenyl-6-[(1S,2R)-(2-phenylcyclohexyl)oxy]- 4-aza-3,5-dioxatricyclo[5.2.1.0^4,9]decane

Julie A. Dixon, Kevin A. Swiss, Scott E. Denmark

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

The structure of the title compound, C₂₆H₃₁NO₃, was determined by X-ray crystallography. It was found to be a unique bridged tricyclic nitroso acetal. Notable features include a chair conformation of the tetrahydro-1,2-oxazine ring and a highly pyramidalized N atom [Σ_angles = 314.2(6)°]. The configurations of the five contiguous stereogenic centers in the nitroso acetal establish that the tandem cycloaddition sequence proceeded via an exo-[4+2]/endo-[3+2] pathway.

Original language	English (US)
Pages (from-to)	2561-2563
Number of pages	3
Journal	Acta Crystallographica Section C: Crystal Structure Communications
Volume	52
Issue number	10
DOIs	https://doi.org/10.1107/S0108270196006671
State	Published - Oct 15 1996

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Online availability

10.1107/S0108270196006671

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Cite this

@article{0fa72a1d2e50454f8bff91253a5e5d1a,

title = "Rel-(1R,6S,7S,8R,9S)-9-methyl-8-phenyl-6-[(1S,2R)-(2-phenylcyclohexyl)oxy]- 4-aza-3,5-dioxatricyclo[5.2.1.04,9]decane",

abstract = "The structure of the title compound, C26H31NO3, was determined by X-ray crystallography. It was found to be a unique bridged tricyclic nitroso acetal. Notable features include a chair conformation of the tetrahydro-1,2-oxazine ring and a highly pyramidalized N atom [Σangles = 314.2(6)°]. The configurations of the five contiguous stereogenic centers in the nitroso acetal establish that the tandem cycloaddition sequence proceeded via an exo-[4+2]/endo-[3+2] pathway.",

author = "Dixon, {Julie A.} and Swiss, {Kevin A.} and Denmark, {Scott E.}",

year = "1996",

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doi = "10.1107/S0108270196006671",

language = "English (US)",

volume = "52",

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journal = "Acta Crystallographica, Section C: Crystal Structure Communications",

issn = "0108-2701",

publisher = "International Union of Crystallography",

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T1 - Rel-(1R,6S,7S,8R,9S)-9-methyl-8-phenyl-6-[(1S,2R)-(2-phenylcyclohexyl)oxy]- 4-aza-3,5-dioxatricyclo[5.2.1.04,9]decane

AU - Dixon, Julie A.

AU - Swiss, Kevin A.

AU - Denmark, Scott E.

PY - 1996/10/15

Y1 - 1996/10/15

N2 - The structure of the title compound, C26H31NO3, was determined by X-ray crystallography. It was found to be a unique bridged tricyclic nitroso acetal. Notable features include a chair conformation of the tetrahydro-1,2-oxazine ring and a highly pyramidalized N atom [Σangles = 314.2(6)°]. The configurations of the five contiguous stereogenic centers in the nitroso acetal establish that the tandem cycloaddition sequence proceeded via an exo-[4+2]/endo-[3+2] pathway.

AB - The structure of the title compound, C26H31NO3, was determined by X-ray crystallography. It was found to be a unique bridged tricyclic nitroso acetal. Notable features include a chair conformation of the tetrahydro-1,2-oxazine ring and a highly pyramidalized N atom [Σangles = 314.2(6)°]. The configurations of the five contiguous stereogenic centers in the nitroso acetal establish that the tandem cycloaddition sequence proceeded via an exo-[4+2]/endo-[3+2] pathway.

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