Rel-(1R,6S,7S,8R,9S)-9-methyl-8-phenyl-6-[(1S,2R)-(2-phenylcyclohexyl)oxy]- 4-aza-3,5-dioxatricyclo[5.2.1.04,9]decane

Julie A. Dixon, Kevin A. Swiss, Scott E. Denmark

Research output: Contribution to journalArticle

Abstract

The structure of the title compound, C26H31NO3, was determined by X-ray crystallography. It was found to be a unique bridged tricyclic nitroso acetal. Notable features include a chair conformation of the tetrahydro-1,2-oxazine ring and a highly pyramidalized N atom [Σangles = 314.2(6)°]. The configurations of the five contiguous stereogenic centers in the nitroso acetal establish that the tandem cycloaddition sequence proceeded via an exo-[4+2]/endo-[3+2] pathway.

Original languageEnglish (US)
Pages (from-to)2561-2563
Number of pages3
JournalActa Crystallographica Section C: Crystal Structure Communications
Volume52
Issue number10
DOIs
StatePublished - Oct 15 1996

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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