TY - JOUR
T1 - Reference point indentation study of age-related changes in porcine femoral cortical bone
AU - Rasoulian, Ramin
AU - Raeisi Najafi, Ahmad
AU - Chittenden, Michael
AU - Jasiuk, Iwona
N1 - Funding Information:
This research was supported by the National Science Foundation ( CMMI 09-27909 ) (I.J.). We thank Alexander Proctor from Active Life Scientific, Inc. for conducting the RPI measurements, and Alexander Proctor and Davis Brimer from Active Life Scientific, Inc. for valuable discussions on the RPI technique. None of the authors have competing interests to declare, financial or otherwise. Ethics approval was not required by our Institutional Review Board.
PY - 2013/6/21
Y1 - 2013/6/21
N2 - The reference point indentation (RPI) method is a microindentation technique involving successive indentation cycles. We employed RPI to measure average stiffness (Ave US), indentation distance increase (IDI), total indentation distance (TID), average energy dissipated (Ave ED), and creep indentation distance (CID) of swine femoral cortical bone (mid-diaphysis) as a function of age (1, 3.5, 6, 14.5, 24, and 48 months) and loading directions (longitudinal and transverse). The Ave US increases with animal age, while the IDI, TID, Ave ED, and CID decrease with age, for both longitudinal (transverse surface) and transverse (periosteal surface) loading directions. Longitudinal measurements generally give higher Ave US and lower IDI and TID values compared to transverse measurements. The RPI measurements show similar trends to those obtained using nanoindentation test, and ash and water content tests.
AB - The reference point indentation (RPI) method is a microindentation technique involving successive indentation cycles. We employed RPI to measure average stiffness (Ave US), indentation distance increase (IDI), total indentation distance (TID), average energy dissipated (Ave ED), and creep indentation distance (CID) of swine femoral cortical bone (mid-diaphysis) as a function of age (1, 3.5, 6, 14.5, 24, and 48 months) and loading directions (longitudinal and transverse). The Ave US increases with animal age, while the IDI, TID, Ave ED, and CID decrease with age, for both longitudinal (transverse surface) and transverse (periosteal surface) loading directions. Longitudinal measurements generally give higher Ave US and lower IDI and TID values compared to transverse measurements. The RPI measurements show similar trends to those obtained using nanoindentation test, and ash and water content tests.
KW - Age
KW - Cortical bone
KW - Indentation distance increase
KW - Loading direction
KW - Microindentation
KW - Reference point indentation
KW - Stiffness
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U2 - 10.1016/j.jbiomech.2013.04.003
DO - 10.1016/j.jbiomech.2013.04.003
M3 - Article
C2 - 23676290
AN - SCOPUS:84886885740
SN - 0021-9290
VL - 46
SP - 1689
EP - 1696
JO - Journal of Biomechanics
JF - Journal of Biomechanics
IS - 10
ER -