@article{9761659d60c047f88d40160a32278bd9,
title = "Recent developments in pretreatment technologies on lignocellulosic biomass: Effect of key parameters, technological improvements, and challenges",
abstract = "Lignocellulosic biomass is an inexpensive renewable source that can be used to produce biofuels and bioproducts. The recalcitrance nature of biomass hampers polysaccharide accessibility for enzymes and microbes. Several pretreatment methods have been developed for the conversion of lignocellulosic biomass into value-added products. However, these pretreatment methods also produce a wide range of secondary compounds, which are inhibitory to enzymes and microorganisms. The selection of an effective and efficient pretreatment method discussed in the review and its process optimization can significantly reduce the production of inhibitory compounds and may lead to enhanced production of fermentable sugars and biochemicals. Moreover, evolutionary and genetic engineering approaches are being used for the improvement of microbial tolerance towards inhibitors. Advancements in pretreatment and detoxification technologies may help to increase the productivity of lignocellulose-based biorefinery. In this review, we discuss the recent advancements in lignocellulosic biomass pretreatment technologies and strategies for the removal of inhibitors.",
keywords = "Biomass, Biorefinery, Detoxification, Inhibition, Lignocellulose, Pretreatment",
author = "Bhatia, {Shashi Kant} and Jagtap, {Sujit Sadashiv} and Bedekar, {Ashwini Ashok} and Bhatia, {Ravi Kant} and Patel, {Anil Kumar} and Deepak Pant and {Rajesh Banu}, J. and Rao, {Christopher V.} and Kim, {Yun Gon} and Yang, {Yung Hun}",
note = "Funding Information: The authors would like to acknowledge the KU Research Professor Program of Konkuk University, Seoul, South Korea. This study was supported by Research Program to solve social issues of the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (2017M3A9E4077234), National Research Foundation of Korea (NRF) (NRF-2015M1A5A1037196, NRF-2019M3E6A1103979, 2017R1D1A1B03030766). In addition, this work was also supported by polar academic program (PAP, PE18900). The consulting service of the Microbial Carbohydrate Resource Bank (MCRB, Seoul, South Korea) is greatly appreciated. This work also supported by the US Department of Energy, Office of Science, Office of Biological and Environmental Research under Award Number(s) DE-SC0018420. University Grant Commission (UGC) New Delhi, India also duly acknowledged for providing financial assistance to Dr. Ravi Kant Bhatia in the form of PDF (No. F./PDFSS201415SCHIM8434). Funding Information: The authors would like to acknowledge the KU Research Professor Program of Konkuk University , Seoul, South Korea. This study was supported by Research Program to solve social issues of the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT ( 2017M3A9E4077234 ), National Research Foundation of Korea (NRF) (NRF-2015M1A5A1037196, NRF-2019M3E6A1103979, 2017R1D1A1B03030766). In addition, this work was also supported by polar academic program (PAP, PE18900). The consulting service of the Microbial Carbohydrate Resource Bank (MCRB, Seoul, South Korea) is greatly appreciated. This work also supported by the US Department of Energy , Office of Science , Office of Biological and Environmental Research under Award Number(s) DE-SC0018420. University Grant Commission (UGC) New Delhi, India also duly acknowledged for providing financial assistance to Dr. Ravi Kant Bhatia in the form of PDF (No. F./PDFSS201415SCHIM8434). Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",
year = "2020",
month = mar,
doi = "10.1016/j.biortech.2019.122724",
language = "English (US)",
volume = "300",
journal = "Bioresource Technology",
issn = "0960-8524",
publisher = "Elsevier Limited",
}