Real-Time Virus Trapping and Fluorescent Imaging in Microfluidic Devices

Demir Akin, Haibo Li, Rashid Bashir

Research output: Contribution to journalArticlepeer-review

Abstract

We have used dielectrophoretic filters within microfluidic biochips to capture from a flow and image virus particles in real-time. The verification of capture was performed by fluorescently labeling the particles using dual or triple labeling. These nonmechanical filters can be very valuable in the sample preparation, purification, and concentration of viral particles from a mixed sample. The described imaging methodology can be used for real-time imaging of nanometer scale virus particles for analysis of capture, detection, and characterization of these particles within micro and nanoscale sensors.

Original languageEnglish (US)
Pages (from-to)257-259
Number of pages3
JournalNano letters
Volume4
Issue number2
DOIs
StatePublished - Feb 2004
Externally publishedYes

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanical Engineering

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