Real-time hyperspectral endoscope for early cancer diagnostics

Robert T. Kester, Liang Gao, Noah Bedard, Tomasz S. Tkaczyk

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Hyperspectral imaging has tremendous potential to detect important molecular biomarkers of early cancer based on their unique spectral signatures. Several drawbacks have limited their use for in vivo screening applications: most notably their poor temporal and spatial resolution, high expense, and low optical throughput. We present the development of a new real-time hyperspectral endoscope (called the IMS Endoscope) based on an image mapping technique which makes it capable of addressing these challenges. The parallel, high throughput nature of this technique enables the device to operate at frame rates of 3-10 fps while collecting a 3D (x, y, λ) datacube of 350 x 350 x 48.

Original languageEnglish (US)
Title of host publicationAdvanced Biomedical and Clinical Diagnostic Systems VIII
StatePublished - May 7 2010
Externally publishedYes
EventAdvanced Biomedical and Clinical Diagnostic Systems VIII - San Francisco, CA, United States
Duration: Jan 24 2010Jan 26 2010

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherAdvanced Biomedical and Clinical Diagnostic Systems VIII
CountryUnited States
CitySan Francisco, CA


  • Endoscope
  • Hyperspectral
  • Image spectrometer
  • Multispectral

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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