Real-time high-resolution measurement of collagen alignment in dynamically loaded soft tissue

Timothy York, Lindsey Kahan, Spencer P. Lake, Viktor Gruev

Research output: Contribution to journalArticlepeer-review

Abstract

A technique for creating maps of the direction and strength of fiber alignment in collagenous soft tissues is presented. The method uses a division of focal plane polarimeter to measure circularly polarized light transmitted through the tissue. The architecture of the sensor allows measurement of the retardance and fiber alignment at the full frame rate of the sensor without any moving optics. The technique compares favorably to the standard method of using a rotating polarizer. How the new technique enables real-time capture of the full angular spread of fiber alignment and retardance under various cyclic loading conditions is illustrated.

Original languageEnglish (US)
Article number066011
JournalJournal of biomedical optics
Volume19
Issue number6
DOIs
StatePublished - Jun 2014
Externally publishedYes

Keywords

  • collagen fiber alignment
  • polarimetric imaging
  • polarimetry
  • polarization
  • soft tissue

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Biomedical Engineering

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