Rapid acquisition of in vivo biological images by use of optical coherence tomography

G. J. Tearney; B. E. Bouma; S. A. Boppart; B. Golubovic; E. A. Swanson; J. G. Fujimoto

doi:10.1364/OL.21.001408

Rapid acquisition of in vivo biological images by use of optical coherence tomography

G. J. Tearney, B. E. Bouma, S. A. Boppart, B. Golubovic, E. A. Swanson, J. G. Fujimoto

Research output: Contribution to journal › Article › peer-review

Abstract

The development of techniques for high-speed image acquisition in optical coherence tomography (OCT) systems is essential for suppressing motion artifacts when one is imaging living systems. We describe a new OCT system for performing micrometer-scale, cross-sectional optical imaging at four images/s. To achieve OCT image-acquisition times of less than 1 s, we use a piezoelectric fiber stretcher to vary the reference arm delay. A Kerr-lens mode-locked chromium-doped forsterite laser is employed as the low-coherence source for the high-speed OCT system. Dynamic, motion-artifact-free in vivo imaging of a beating Xenopus laevis (African frog) heart is demonstrated.

Original language	English (US)
Pages (from-to)	1408-1410
Number of pages	3
Journal	Optics Letters
Volume	21
Issue number	17
DOIs	https://doi.org/10.1364/OL.21.001408
State	Published - Oct 1 1996
Externally published	Yes

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

Online availability

10.1364/OL.21.001408

Library availability

Discover UIUC Full Text

Cite this

@article{d1c94a5b3b724d2d9128977ebb94210e,

title = "Rapid acquisition of in vivo biological images by use of optical coherence tomography",

abstract = "The development of techniques for high-speed image acquisition in optical coherence tomography (OCT) systems is essential for suppressing motion artifacts when one is imaging living systems. We describe a new OCT system for performing micrometer-scale, cross-sectional optical imaging at four images/s. To achieve OCT image-acquisition times of less than 1 s, we use a piezoelectric fiber stretcher to vary the reference arm delay. A Kerr-lens mode-locked chromium-doped forsterite laser is employed as the low-coherence source for the high-speed OCT system. Dynamic, motion-artifact-free in vivo imaging of a beating Xenopus laevis (African frog) heart is demonstrated.",

author = "Tearney, {G. J.} and Bouma, {B. E.} and Boppart, {S. A.} and B. Golubovic and Swanson, {E. A.} and Fujimoto, {J. G.}",

year = "1996",

month = oct,

day = "1",

doi = "10.1364/OL.21.001408",

language = "English (US)",

volume = "21",

pages = "1408--1410",

journal = "Optics Letters",

issn = "0146-9592",

publisher = "The Optical Society",

number = "17",

}

TY - JOUR

T1 - Rapid acquisition of in vivo biological images by use of optical coherence tomography

AU - Tearney, G. J.

AU - Bouma, B. E.

AU - Boppart, S. A.

AU - Golubovic, B.

AU - Swanson, E. A.

AU - Fujimoto, J. G.

PY - 1996/10/1

Y1 - 1996/10/1

N2 - The development of techniques for high-speed image acquisition in optical coherence tomography (OCT) systems is essential for suppressing motion artifacts when one is imaging living systems. We describe a new OCT system for performing micrometer-scale, cross-sectional optical imaging at four images/s. To achieve OCT image-acquisition times of less than 1 s, we use a piezoelectric fiber stretcher to vary the reference arm delay. A Kerr-lens mode-locked chromium-doped forsterite laser is employed as the low-coherence source for the high-speed OCT system. Dynamic, motion-artifact-free in vivo imaging of a beating Xenopus laevis (African frog) heart is demonstrated.

AB - The development of techniques for high-speed image acquisition in optical coherence tomography (OCT) systems is essential for suppressing motion artifacts when one is imaging living systems. We describe a new OCT system for performing micrometer-scale, cross-sectional optical imaging at four images/s. To achieve OCT image-acquisition times of less than 1 s, we use a piezoelectric fiber stretcher to vary the reference arm delay. A Kerr-lens mode-locked chromium-doped forsterite laser is employed as the low-coherence source for the high-speed OCT system. Dynamic, motion-artifact-free in vivo imaging of a beating Xenopus laevis (African frog) heart is demonstrated.

UR - http://www.scopus.com/inward/record.url?scp=0000950968&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0000950968&partnerID=8YFLogxK

U2 - 10.1364/OL.21.001408

DO - 10.1364/OL.21.001408

M3 - Article

C2 - 19876368

AN - SCOPUS:0000950968

SN - 0146-9592

VL - 21

SP - 1408

EP - 1410

JO - Optics Letters

JF - Optics Letters

IS - 17

ER -

Rapid acquisition of in vivo biological images by use of optical coherence tomography

Abstract

ASJC Scopus subject areas

Online availability

Library availability

Related links

Fingerprint

Cite this