Rapid acquisition of in vivo biological images by use of optical coherence tomography

G. J. Tearney, B. E. Bouma, S. A. Boppart, B. Golubovic, E. A. Swanson, J. G. Fujimoto

Research output: Contribution to journalArticlepeer-review

Abstract

The development of techniques for high-speed image acquisition in optical coherence tomography (OCT) systems is essential for suppressing motion artifacts when one is imaging living systems. We describe a new OCT system for performing micrometer-scale, cross-sectional optical imaging at four images/s. To achieve OCT image-acquisition times of less than 1 s, we use a piezoelectric fiber stretcher to vary the reference arm delay. A Kerr-lens mode-locked chromium-doped forsterite laser is employed as the low-coherence source for the high-speed OCT system. Dynamic, motion-artifact-free in vivo imaging of a beating Xenopus laevis (African frog) heart is demonstrated.

Original languageEnglish (US)
Pages (from-to)1408-1410
Number of pages3
JournalOptics Letters
Volume21
Issue number17
DOIs
StatePublished - Oct 1 1996
Externally publishedYes

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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