Qualitative and quantitative tear film abnormalities in dogs

Alexandre Pinto Ribeiro, Fabio Luiz Da Cunha Brito, Bianca Da Costa Martins, Fabrício Mamede, José Luiz Laus

Research output: Contribution to journalReview articlepeer-review


Tear film disorders in dogs can be classified into quantitative or qualitative abnormalities, or both, and are commonly observed in daily clinical practice. Inadequate production of one or more tear film components can lead to variable degrees of ocular disorders, called keratoconjunctivitis sicca. Keratoconjunctivitis sicca in dogs has several causes, but in most cases the disease is idiopathic, with T lymphocytes playing a role. In veterinary medicine, the diagnosis is made based on the results of the Schirmer tear test. In this article, we review aspects related to the etiopathogenesis and diagnosis of keratoconjunctivitis sicca in dogs and discuss new therapeutic modalities for this disease.

Original languageEnglish (US)
Pages (from-to)568-575
Number of pages8
JournalCiencia Rural
Issue number2
StatePublished - Mar 2008
Externally publishedYes


  • Dogs
  • Immunosuppressors
  • Keratoconjunctivitis sicca
  • Lacrimomimetics
  • Lacrimostimulants
  • Tear film

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Agronomy and Crop Science
  • veterinary(all)


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