TY - GEN
T1 - Protein tertiary structure recognition using optimized associative memory Hamiltonians
AU - Goldstein, Richard A.
AU - Luthey-Schulten, Zaida A.
AU - Wolynes, Peter G.
N1 - Publisher Copyright:
© 1993 IEEE.
PY - 1993
Y1 - 1993
N2 - Protein folding codes can be optimized using spin-glass theory. Simple optimal codes are deduced for associative memory Hamiltonians based on aligned sequences. The authors demonstrate the use of associate memory Hamiltonians and show how, with the use of spin-glass theory to provide optimization, and standard alignment methods, it is possible to generate an algorithm that correctly identifies structurally similar proteins in the vast majority of cases.
AB - Protein folding codes can be optimized using spin-glass theory. Simple optimal codes are deduced for associative memory Hamiltonians based on aligned sequences. The authors demonstrate the use of associate memory Hamiltonians and show how, with the use of spin-glass theory to provide optimization, and standard alignment methods, it is possible to generate an algorithm that correctly identifies structurally similar proteins in the vast majority of cases.
UR - http://www.scopus.com/inward/record.url?scp=84995114109&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84995114109&partnerID=8YFLogxK
U2 - 10.1109/HICSS.1993.270671
DO - 10.1109/HICSS.1993.270671
M3 - Conference contribution
AN - SCOPUS:84995114109
T3 - Proceedings of the Annual Hawaii International Conference on System Sciences
SP - 699
EP - 707
BT - Proceedings of the 26th Hawaii International Conference on System Sciences, HICSS 1993
PB - IEEE Computer Society
T2 - 26th Hawaii International Conference on System Sciences, HICSS 1993
Y2 - 8 January 1993
ER -