Protein synthesis with isolated mitochondrial polysomes

N. G. Avadhani, D. E. Buetow

Research output: Contribution to journalArticlepeer-review

Abstract

A technique has been described for the isolation of intact mitochondrial polysomes which are active in protein synthesis. Mitochondrial ribosomes, derived from the polysomes, are of 71S particles and have 32S and 50S subunits. These subunits can initiate protein synthesis using mitochondrial RNA as a template. It is, thus, evident that mitochondria contain active messengers in the process of translation. The translational machinery in this organelle is prokaryotic in nature.

Original languageEnglish (US)
Pages (from-to)773-778
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume46
Issue number2
DOIs
StatePublished - Jan 31 1972

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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