Abstract
Small molecules were created by diversity-oriented synthesis and subsequently subjected to microarray-based screening for their ability to bind a protein of interest. This general two-step method proved powerful in generating highly specific modulators of protein function.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 543-544 |
| Number of pages | 2 |
| Journal | Chemistry and Biology |
| Volume | 9 |
| Issue number | 5 |
| DOIs | |
| State | Published - 2002 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Medicine
- Molecular Biology
- Pharmacology
- Drug Discovery
- Clinical Biochemistry