Protein modulators made to order

Research output: Contribution to journalReview articlepeer-review

Abstract

Small molecules were created by diversity-oriented synthesis and subsequently subjected to microarray-based screening for their ability to bind a protein of interest. This general two-step method proved powerful in generating highly specific modulators of protein function.

Original languageEnglish (US)
Pages (from-to)543-544
Number of pages2
JournalChemistry and Biology
Volume9
Issue number5
DOIs
StatePublished - 2002

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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