Properties and biosynthesis of cyclopropane fatty acids in Escherichia coli

J. E. Cronan, R. Reed, F. R. Taylor, M. B. Jackson

Research output: Contribution to journalArticlepeer-review


The lipid phase transition of E. coli phospholipids containing cyclopropane fatty acids was compared with the otherwise homologous phospholipids lacking cyclopropane fatty acids. The phase transitions (determined by scanning calorimetry) of the two preparations were essentially identical. Infection of E. coli with phage T3 inhibited cyclopropane fatty acid formation over 98%, whereas infection with mutants which lack the phage coded S-adenosylmethionine cleavage enzyme had no effect on cyclopropane fatty acid synthesis. These data indicate that S-adenosylmethionine is the methylene donor in cyclopropane fatty acid synthesis.

Original languageEnglish (US)
Pages (from-to)118-121
Number of pages4
JournalJournal of bacteriology
Issue number1
StatePublished - 1979

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology


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