Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: In vivo and in vitro evidence

Medicine and Dentistry

• In Vitro 100%
• Fibroblast 100%
• Malignant Neoplasm 100%
• Cancer Cell 100%
• Nevus 100%
• Cancer Resistance 100%
• Neoplasm 57%
• Carcinogen 28%
• Hypoxia 28%
• Agar 28%
• Acetic Acid 28%
• 7,12 Dimethylbenz[a]anthracene 28%
• Disease 14%
• Cell Viability 14%
• Carcinogenesis 14%
• Cancer 14%
• Cell Interaction 14%
• Colony Formation 14%
• Cancer Cell Line 14%
• Cell Cycle Progression 14%
• Antineoplastic Activity 14%
• Host Resistance 14%
• Experimental Neoplasm 14%
• Chromatin Condensation 14%

Keyphrases

• Blind Mole Rat 100%
• Spalax 100%
• Subterranean Rodents 100%
• Cancer Resistance 100%
• Cancer Cells 29%
• Fibroblasts 17%
• Tumor 11%
• Soft Agar 11%
• Chemically Induced 11%
• Skin Fibroblasts 11%
• Soluble Factors 11%
• Anticancer Activity 11%
• Phorbol 12-myristate 13-acetate 11%
• Carcinogen 11%
• 7,12-dimethylbenz(a)anthracene 11%
• Culture Media 5%
• Rodents 5%
• Molecular Mechanism 5%
• Direct Interaction 5%
• Extreme Environments 5%
• Age Groups 5%
• Malignancy 5%
• Cancer Cell Lines 5%
• Tumorigenesis 5%
• Cell Cycle Progression 5%
• Long-lived 5%
• In Vitro Experiment 5%
• Colony Formation 5%
• High Resistance 5%
• Advanced Age 5%
• Non-cancer 5%
• Spontaneous Tumors 5%
• Suppressive Activity 5%
• Tumor Suppression 5%
• Anticancer Strategy 5%
• Chromatin Condensation 5%
• Age-related Illnesses 5%
• Host Resistance 5%
• Cultured Fibroblasts 5%
• Hypoxia-tolerant 5%
• Cancer Cell Interactions 5%
• Subterranean Mammals 5%
• Naked Mole-rat 5%
• Adaptation to Hypoxia 5%
• Fibroblast-conditioned Media 5%
• Acomys 5%
• Fibroblastic Proliferation 5%
• Cancer Cell Viability 5%
• Malignant Behavior 5%
• Mitochondrial Fragmentation 5%
• Spontaneous Cancer 5%
• Signs of Aging 5%

Pharmacology, Toxicology and Pharmaceutical Science

• Spalax 100%
• Cancer Resistance 100%
• Malignant Neoplasm 84%
• Neoplasm 21%
• Mouse 10%
• Hypoxia 10%
• Agar 10%
• 12-O-Tetradecanoylphorbol-13-Acetate 10%
• Carcinogen 10%
• 7,12-Dimethylbenz(a)anthracene 10%
• Disease 5%
• Cell Viability 5%
• Carcinogenesis 5%
• Experimental Neoplasm 5%
• Heterocephalus 5%
• Acomys 5%