Production of lantipeptides in Escherichia coli

Yanxiang Shi, Xiao Yang, Neha Garg, Wilfred A. Van Der Donk

Research output: Contribution to journalArticlepeer-review

Abstract

Lantipeptides are ribosomally synthesized and posttranslationally modified peptides containing thioether cross-links. We describe the preparation of seven different lantipeptides in Escherichia coli and demonstrate that this methodology can be used to incorporate nonproteinogenic amino acids.

Original languageEnglish (US)
Pages (from-to)2338-2341
Number of pages4
JournalJournal of the American Chemical Society
Volume133
Issue number8
DOIs
StatePublished - Mar 2 2011

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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