Proceedings of the 2017 National Toxicology Program Satellite Symposium

Susan A. Elmore, Famke Aeffner, Dinesh S. Bangari, Torrie A. Crabbs, Stacey Fossey, Shayne C. Gad, Wanda M. Haschek, Jessica S. Hoane, Kyathanahalli Janardhan, Ramesh C. Kovi, Gail Pearse, Lyn M. Wancket, Erin M. Quist

Research output: Contribution to journalArticle

Abstract

The 2017 annual National Toxicology Program Satellite Symposium, entitled “Pathology Potpourri,” was held in Montreal, Quebec, Canada at the Society of Toxicologic Pathology’s 36th annual meeting. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers’ talks along with select images that were used by the audience for voting and discussion. Various lesions and other topics covered during the symposium included renal papillary degeneration in perinatally exposed animals, an atriocaval mesothelioma, an unusual presentation of an alveolar–bronchiolar carcinoma, a paraganglioma of the organ of Zuckerkandl (also called an extra-adrenal pheochromocytoma), the use of human muscle samples to illustrate the challenges of manual scoring of fluorescent staining, intertubular spermatocytic seminomas, medical device pathology assessment and discussion of the approval process, collagen-induced arthritis, incisor denticles, ameloblast degeneration and poorly mineralized enamel matrix, connective tissue paragangliomas, microcystin-LR toxicity, perivascular mast cells in the forebrain thalamus unrelated to treatment, and 2 cases that provided a review of the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) bone nomenclature and recommended application of the terminology in routine nonclinical toxicity studies.

Original languageEnglish (US)
Pages (from-to)799-833
Number of pages35
JournalToxicologic Pathology
Volume45
Issue number7
DOIs
StatePublished - Oct 1 2017

Keywords

  • INHAND
  • NTP Satellite Symposium
  • atriocaval mesothelioma
  • collagen-induced arthritis model
  • digital image analysis
  • incisor denticle
  • medical device evaluation
  • microcystin-LR
  • neural mast cells
  • paraganglioma
  • perinatal nephrotoxicosis
  • spermatocytic seminoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Molecular Biology
  • Toxicology
  • Cell Biology

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  • Cite this

    Elmore, S. A., Aeffner, F., Bangari, D. S., Crabbs, T. A., Fossey, S., Gad, S. C., Haschek, W. M., Hoane, J. S., Janardhan, K., Kovi, R. C., Pearse, G., Wancket, L. M., & Quist, E. M. (2017). Proceedings of the 2017 National Toxicology Program Satellite Symposium. Toxicologic Pathology, 45(7), 799-833. https://doi.org/10.1177/0192623317733924