TY - JOUR
T1 - Proceedings of the 2017 National Toxicology Program Satellite Symposium
AU - Elmore, Susan A.
AU - Aeffner, Famke
AU - Bangari, Dinesh S.
AU - Crabbs, Torrie A.
AU - Fossey, Stacey
AU - Gad, Shayne C.
AU - Haschek, Wanda M.
AU - Hoane, Jessica S.
AU - Janardhan, Kyathanahalli
AU - Kovi, Ramesh C.
AU - Pearse, Gail
AU - Wancket, Lyn M.
AU - Quist, Erin M.
N1 - Publisher Copyright:
© 2017, © The Author(s) 2017.
PY - 2017/10/1
Y1 - 2017/10/1
N2 - The 2017 annual National Toxicology Program Satellite Symposium, entitled “Pathology Potpourri,” was held in Montreal, Quebec, Canada at the Society of Toxicologic Pathology’s 36th annual meeting. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers’ talks along with select images that were used by the audience for voting and discussion. Various lesions and other topics covered during the symposium included renal papillary degeneration in perinatally exposed animals, an atriocaval mesothelioma, an unusual presentation of an alveolar–bronchiolar carcinoma, a paraganglioma of the organ of Zuckerkandl (also called an extra-adrenal pheochromocytoma), the use of human muscle samples to illustrate the challenges of manual scoring of fluorescent staining, intertubular spermatocytic seminomas, medical device pathology assessment and discussion of the approval process, collagen-induced arthritis, incisor denticles, ameloblast degeneration and poorly mineralized enamel matrix, connective tissue paragangliomas, microcystin-LR toxicity, perivascular mast cells in the forebrain thalamus unrelated to treatment, and 2 cases that provided a review of the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) bone nomenclature and recommended application of the terminology in routine nonclinical toxicity studies.
AB - The 2017 annual National Toxicology Program Satellite Symposium, entitled “Pathology Potpourri,” was held in Montreal, Quebec, Canada at the Society of Toxicologic Pathology’s 36th annual meeting. The goal of this symposium was to present and discuss challenging diagnostic pathology and/or nomenclature issues. This article presents summaries of the speakers’ talks along with select images that were used by the audience for voting and discussion. Various lesions and other topics covered during the symposium included renal papillary degeneration in perinatally exposed animals, an atriocaval mesothelioma, an unusual presentation of an alveolar–bronchiolar carcinoma, a paraganglioma of the organ of Zuckerkandl (also called an extra-adrenal pheochromocytoma), the use of human muscle samples to illustrate the challenges of manual scoring of fluorescent staining, intertubular spermatocytic seminomas, medical device pathology assessment and discussion of the approval process, collagen-induced arthritis, incisor denticles, ameloblast degeneration and poorly mineralized enamel matrix, connective tissue paragangliomas, microcystin-LR toxicity, perivascular mast cells in the forebrain thalamus unrelated to treatment, and 2 cases that provided a review of the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) bone nomenclature and recommended application of the terminology in routine nonclinical toxicity studies.
KW - INHAND
KW - NTP Satellite Symposium
KW - atriocaval mesothelioma
KW - collagen-induced arthritis model
KW - digital image analysis
KW - incisor denticle
KW - medical device evaluation
KW - microcystin-LR
KW - neural mast cells
KW - paraganglioma
KW - perinatal nephrotoxicosis
KW - spermatocytic seminoma
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U2 - 10.1177/0192623317733924
DO - 10.1177/0192623317733924
M3 - Article
C2 - 29113559
AN - SCOPUS:85034989416
SN - 0192-6233
VL - 45
SP - 799
EP - 833
JO - Toxicologic Pathology
JF - Toxicologic Pathology
IS - 7
ER -