Procaspase combination therapy for glioblastoma

Paul J Hergenrother; Rachel C Botham; Timothy M Fan; Mark John Gilbert; Michael Kevin Handley; Avadhut Joshi; Gregory J Riggins; Theodore M. Tarasow

Procaspase combination therapy for glioblastoma

Paul J Hergenrother (Inventor), Rachel C Botham (Inventor), Timothy M Fan (Inventor), Mark John Gilbert (Inventor), Michael Kevin Handley (Inventor), Avadhut Joshi (Inventor), Gregory J Riggins (Inventor), Theodore M. Tarasow (Inventor)

Research output: Patent

Abstract

The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.

Original language	English (US)
U.S. patent number	9421202
State	Published - Aug 23 2016

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title = "Procaspase combination therapy for glioblastoma",

abstract = "The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.",

author = "Hergenrother, {Paul J} and Botham, {Rachel C} and Fan, {Timothy M} and Gilbert, {Mark John} and Handley, {Michael Kevin} and Avadhut Joshi and Riggins, {Gregory J} and Tarasow, {Theodore M.}",

year = "2016",

month = aug,

day = "23",

language = "English (US)",

type = "Patent",

note = "9421202",

}

TY - PAT

T1 - Procaspase combination therapy for glioblastoma

AU - Hergenrother, Paul J

AU - Botham, Rachel C

AU - Fan, Timothy M

AU - Gilbert, Mark John

AU - Handley, Michael Kevin

AU - Joshi, Avadhut

AU - Riggins, Gregory J

AU - Tarasow, Theodore M.

PY - 2016/8/23

Y1 - 2016/8/23

N2 - The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.

AB - The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.

M3 - Patent

M1 - 9421202

ER -

Procaspase combination therapy for glioblastoma

Abstract

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