Probing DNA structure with nanoparticles.

Rahina Mahtab; Catherine J. Murphy

doi:10.1385/1-59259-901-x:179

Probing DNA structure with nanoparticles.

Rahina Mahtab
, Catherine J. Murphy

Research output: Contribution to journal › Article › peer-review

Abstract

Semiconductor nanoparticles, also known as quantum dots, are receiving increasing attention for their biological applications. These nanomaterials are photoluminescent and are being developed both as dyes and as sensors. Here we describe our "sensor" use of quantum dots to detect different intrinsic DNA structures. Structural polymorphism in DNA may serve as a biological signal in vivo, highlighting the need for recognition of DNA structure in addition to DNA sequence in biotechnology assays.

Original language	English (US)
Pages (from-to)	179-190
Number of pages	12
Journal	Methods in molecular biology (Clifton, N.J.)
Volume	303
DOIs	https://doi.org/10.1385/1-59259-901-x:179
State	Published - 2005
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Genetics

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title = "Probing DNA structure with nanoparticles.",

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AU - Murphy, Catherine J.

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AB - Semiconductor nanoparticles, also known as quantum dots, are receiving increasing attention for their biological applications. These nanomaterials are photoluminescent and are being developed both as dyes and as sensors. Here we describe our "sensor" use of quantum dots to detect different intrinsic DNA structures. Structural polymorphism in DNA may serve as a biological signal in vivo, highlighting the need for recognition of DNA structure in addition to DNA sequence in biotechnology assays.

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UR - https://www.scopus.com/pages/publications/22844431718#tab=citedBy

U2 - 10.1385/1-59259-901-x:179

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M3 - Article

C2 - 15923684

AN - SCOPUS:22844431718

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JO - Methods in molecular biology (Clifton, N.J.)

JF - Methods in molecular biology (Clifton, N.J.)

ER -

Probing DNA structure with nanoparticles.

Abstract

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