TY - JOUR
T1 - Probing DNA structure with nanoparticles.
AU - Mahtab, Rahina
AU - Murphy, Catherine J.
PY - 2005
Y1 - 2005
N2 - Semiconductor nanoparticles, also known as quantum dots, are receiving increasing attention for their biological applications. These nanomaterials are photoluminescent and are being developed both as dyes and as sensors. Here we describe our "sensor" use of quantum dots to detect different intrinsic DNA structures. Structural polymorphism in DNA may serve as a biological signal in vivo, highlighting the need for recognition of DNA structure in addition to DNA sequence in biotechnology assays.
AB - Semiconductor nanoparticles, also known as quantum dots, are receiving increasing attention for their biological applications. These nanomaterials are photoluminescent and are being developed both as dyes and as sensors. Here we describe our "sensor" use of quantum dots to detect different intrinsic DNA structures. Structural polymorphism in DNA may serve as a biological signal in vivo, highlighting the need for recognition of DNA structure in addition to DNA sequence in biotechnology assays.
UR - https://www.scopus.com/pages/publications/22844431718
UR - https://www.scopus.com/inward/citedby.url?scp=22844431718&partnerID=8YFLogxK
U2 - 10.1385/1-59259-901-x:179
DO - 10.1385/1-59259-901-x:179
M3 - Article
C2 - 15923684
AN - SCOPUS:22844431718
SN - 1064-3745
VL - 303
SP - 179
EP - 190
JO - Methods in molecular biology (Clifton, N.J.)
JF - Methods in molecular biology (Clifton, N.J.)
ER -