Abstract
This chapter traces the historical development of Lewis's concepts of acids and bases, to chronicle various refinements and presents a number of modern interpretations of donor-acceptor interactions. It provides a conceptual framework that allows a clear formulation of what exactly "Lewis base catalysis" constitutes. As the application of quantum mechanics became more and more important to understanding structure and reactivity of organic molecules, the need to adapt Lewis's definitions of acids and bases in terms of molecular orbital theory became apparent. The expression of the interaction in quantum-mechanical terminology allowed R.S. Mulliken to recognize a number of significant consequences that were inaccessible to Lewis and his successors because of the limitations of earlier structural theories. The chapter also explores the most successful analyses beginning with an expanded presentation of the Mulliken valence bond approach through primarily empirical to highly theoretical analyses.
| Original language | English (US) |
|---|---|
| Title of host publication | Lewis Base Catalysis in Organic Synthesis |
| Publisher | Wiley-VCH Verlag |
| Pages | 33-54 |
| Number of pages | 22 |
| Volume | 1 |
| ISBN (Electronic) | 9783527675142 |
| ISBN (Print) | 9783527336180 |
| DOIs | |
| State | Published - Aug 17 2016 |
Fingerprint
Keywords
- Lewis acid-Lewis base interactions
- Lewis base catalysis
- Molecular orbital theory
- Mulliken valence bond approach
- Quantum mechanics
- Quantum-mechanical terminology
ASJC Scopus subject areas
- Chemistry(all)
Cite this
Principles, Definitions, Terminology, and Orbital Analysis of Lewis Base-Lewis Acid Interactions Leading to Catalysis. / Denmark, Scott E; Beutner, Gregory L.
Lewis Base Catalysis in Organic Synthesis. Vol. 1 Wiley-VCH Verlag, 2016. p. 33-54.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Principles, Definitions, Terminology, and Orbital Analysis of Lewis Base-Lewis Acid Interactions Leading to Catalysis
AU - Denmark, Scott E
AU - Beutner, Gregory L.
PY - 2016/8/17
Y1 - 2016/8/17
N2 - This chapter traces the historical development of Lewis's concepts of acids and bases, to chronicle various refinements and presents a number of modern interpretations of donor-acceptor interactions. It provides a conceptual framework that allows a clear formulation of what exactly "Lewis base catalysis" constitutes. As the application of quantum mechanics became more and more important to understanding structure and reactivity of organic molecules, the need to adapt Lewis's definitions of acids and bases in terms of molecular orbital theory became apparent. The expression of the interaction in quantum-mechanical terminology allowed R.S. Mulliken to recognize a number of significant consequences that were inaccessible to Lewis and his successors because of the limitations of earlier structural theories. The chapter also explores the most successful analyses beginning with an expanded presentation of the Mulliken valence bond approach through primarily empirical to highly theoretical analyses.
AB - This chapter traces the historical development of Lewis's concepts of acids and bases, to chronicle various refinements and presents a number of modern interpretations of donor-acceptor interactions. It provides a conceptual framework that allows a clear formulation of what exactly "Lewis base catalysis" constitutes. As the application of quantum mechanics became more and more important to understanding structure and reactivity of organic molecules, the need to adapt Lewis's definitions of acids and bases in terms of molecular orbital theory became apparent. The expression of the interaction in quantum-mechanical terminology allowed R.S. Mulliken to recognize a number of significant consequences that were inaccessible to Lewis and his successors because of the limitations of earlier structural theories. The chapter also explores the most successful analyses beginning with an expanded presentation of the Mulliken valence bond approach through primarily empirical to highly theoretical analyses.
KW - Lewis acid-Lewis base interactions
KW - Lewis base catalysis
KW - Molecular orbital theory
KW - Mulliken valence bond approach
KW - Quantum mechanics
KW - Quantum-mechanical terminology
UR - http://www.scopus.com/inward/record.url?scp=85018351686&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85018351686&partnerID=8YFLogxK
U2 - 10.1002/9783527675142.ch2
DO - 10.1002/9783527675142.ch2
M3 - Chapter
AN - SCOPUS:85018351686
SN - 9783527336180
VL - 1
SP - 33
EP - 54
BT - Lewis Base Catalysis in Organic Synthesis
PB - Wiley-VCH Verlag
ER -