TY - JOUR
T1 - Prepregnancy maternal BMI and trajectories of BMI-for-age in children up to four years of age
T2 - findings from the 2015 Pelotas (Brazil) birth cohort
AU - Flores, Thaynã R.
AU - de Andrade Leão, Otávio Amaral
AU - Nunes, Bruno P.
AU - Mielke, Gregore Iven
AU - dos Santos Costa, Caroline
AU - Buffarini, Romina
AU - Domingues, Marlos Rodrigues
AU - da Silveira, Mariangela Freitas
AU - Hallal, Pedro C.
AU - Bertoldi, Andréa Dâmaso
N1 - This article is based on data from the study “Pelotas Birth Cohort, 2015” conducted by Postgraduate Program in Epidemiology at Universidade Federal de Pelotas, with the collaboration of the Brazilian Public Health Association (ABRASCO). The first phases of the 2015 Pelotas (Brazil) Birth Cohort was funded by the Wellcome Trust (095582). Funding for specific follow-up visits was also received from the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Fundação de Amparo a Pesquisa do Estado do Rio Grande do Sul (FAPERGS) and Children’s Pastorate sponsored follow-up at twenty-four months; and FAPERGS – PPSUS, the Wellcome Trust (10735_Z_18_Z), and the Bernard van Leer Foundation (BRA-2018-178) for the fort-eight months follow-up.
This article is based on data from the study “Pelotas Birth Cohort, 2015” conducted by Postgraduate Program in Epidemiology at Universidade Federal de Pelotas, with the collaboration of the Brazilian Public Health Association (ABRASCO). The first phases of the 2015 Pelotas (Brazil) Birth Cohort was funded by the Wellcome Trust (095582). Funding for specific follow-up visits was also received from the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Fundação de Amparo a Pesquisa do Estado do Rio Grande do Sul (FAPERGS) and Children’s Pastorate sponsored follow-up at twenty-four months; and FAPERGS – PPSUS, the Wellcome Trust (10735_Z_18_Z), and the Bernard van Leer Foundation (BRA-2018-178) for the fort-eight months follow-up.
PY - 2024/3
Y1 - 2024/3
N2 - Background: The aims of the study were to: (a) describe BMI-for-age trajectories in children up to four years of age; (b) evaluate the association between prepregnancy maternal BMI and the BMI-for-age trajectories. Methods: Data from 3218 (75.3% of the original cohort) children from the Pelotas 2015 Birth Cohort were analyzed. Prepregnancy BMI (kg/m2) was measured on the perinatal interview. Z-scores of BMI-for-age were calculated for children at three months, 1, 2 and 4 years. Trajectories were identified using a semi-parametric group-based modeling approach. Multinomial logistic regression was used to test the association between prepregnancy BMI (weight excess: BMI ≥ 25 kg/m2) and BMI-for-age trajectories. Results: Four trajectories of the BMI-for-age, in z-score, were identified and represent children in the “increasing”, “adequate”, “stabilized” and “risk for weight excess” group. A total of 196 children (7.1%) belonged to the group that was at risk of weight excess. Adjusted analyses showed that children whose mothers presented prepregnancy weight excess had 2.36 (95%CI 1.71; 3.24) times more risk of belonging to group “risk for weight excess” when compared to those children whose mothers presented underweight/normal weight before pregnancy. Conclusion: The risk of weight excess in children up to 4 years of age were greater in mothers who presented prepregnancy weight excess.
AB - Background: The aims of the study were to: (a) describe BMI-for-age trajectories in children up to four years of age; (b) evaluate the association between prepregnancy maternal BMI and the BMI-for-age trajectories. Methods: Data from 3218 (75.3% of the original cohort) children from the Pelotas 2015 Birth Cohort were analyzed. Prepregnancy BMI (kg/m2) was measured on the perinatal interview. Z-scores of BMI-for-age were calculated for children at three months, 1, 2 and 4 years. Trajectories were identified using a semi-parametric group-based modeling approach. Multinomial logistic regression was used to test the association between prepregnancy BMI (weight excess: BMI ≥ 25 kg/m2) and BMI-for-age trajectories. Results: Four trajectories of the BMI-for-age, in z-score, were identified and represent children in the “increasing”, “adequate”, “stabilized” and “risk for weight excess” group. A total of 196 children (7.1%) belonged to the group that was at risk of weight excess. Adjusted analyses showed that children whose mothers presented prepregnancy weight excess had 2.36 (95%CI 1.71; 3.24) times more risk of belonging to group “risk for weight excess” when compared to those children whose mothers presented underweight/normal weight before pregnancy. Conclusion: The risk of weight excess in children up to 4 years of age were greater in mothers who presented prepregnancy weight excess.
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U2 - 10.1038/s41366-023-01422-1
DO - 10.1038/s41366-023-01422-1
M3 - Article
C2 - 38092956
AN - SCOPUS:85179328174
SN - 0307-0565
VL - 48
SP - 353
EP - 359
JO - International Journal of Obesity
JF - International Journal of Obesity
IS - 3
ER -