Preparation of Structurally Diverse Compounds from the Natural Product Lycorine

Sarah Z. Tasker, Amanda E. Cowfer, Paul J. Hergenrother

Research output: Contribution to journalArticle

Abstract

The synthesis of a 52-member compound collection from the natural product lycorine is reported, highlighted by divergent cross-coupling and substitution strategies and an unusual ring rearrangement induced by reaction with aryne intermediates.

Original languageEnglish (US)
Pages (from-to)5894-5898
Number of pages5
JournalOrganic Letters
Volume20
Issue number18
DOIs
StatePublished - Sep 21 2018

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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