Porphyric insecticides. 2. 1,10-Phenanthroline, a potent porphyric insecticide modulator

Constantin A. Rebeiz, John A Juvik, Carole C. Rebeiz, Carl E. Bouton, Larry J. Gut

Research output: Contribution to journalArticle

Abstract

It is shown that in Trichoplusia ni, 1,10-phenanthroline, in addition to 2,2′-dipyridyl, exhibits potent contact porphyric insecticidal modulating properties. When sprayed with δ-aminolevulinic acid, 1,10-phenanthroline causes the larvae to accumulate massive amounts of protoporphyrin IX and lesser amounts of Zn-protoporphyrin IX in darkness and results in insect death in the light. In addition, ingestion of δ-aminolevulinic acid and 1,10-phenanthroline with the diet was extremely efficient in causing tetrapyrrole accumulation in darkness. This tetrapyrrole accumulation, in turn, was extremely efficient at producing insect death in the light, as evidenced by the low concentrations of δ-aminolevulinic acid (2 mM) and 1,10-phenanthroline (0.2 mM) that were sufficient to cause 100% larval mortality. Several substituted 2,2′-dipyridyls and 1,10-phenanthrolines were also shown to act in concert with δ-aminolevulinic acid in causing larval death in the light.

Original languageEnglish (US)
Pages (from-to)201-207
Number of pages7
JournalPesticide Biochemistry and Physiology
Volume36
Issue number2
DOIs
StatePublished - Feb 1990

Fingerprint

aminolevulinic acid
Insecticides
Aminolevulinic Acid
insecticides
protoporphyrin
Tetrapyrroles
death
Darkness
Light
Insects
insecticidal properties
insects
Trichoplusia ni
ingestion
Larva
Eating
1,10-phenanthroline
larvae
Diet
diet

ASJC Scopus subject areas

  • Agronomy and Crop Science
  • Health, Toxicology and Mutagenesis

Cite this

Porphyric insecticides. 2. 1,10-Phenanthroline, a potent porphyric insecticide modulator. / Rebeiz, Constantin A.; Juvik, John A; Rebeiz, Carole C.; Bouton, Carl E.; Gut, Larry J.

In: Pesticide Biochemistry and Physiology, Vol. 36, No. 2, 02.1990, p. 201-207.

Research output: Contribution to journalArticle

Rebeiz, Constantin A. ; Juvik, John A ; Rebeiz, Carole C. ; Bouton, Carl E. ; Gut, Larry J. / Porphyric insecticides. 2. 1,10-Phenanthroline, a potent porphyric insecticide modulator. In: Pesticide Biochemistry and Physiology. 1990 ; Vol. 36, No. 2. pp. 201-207.
@article{37ea1be927434cb3bf343b2bfd7c68c9,
title = "Porphyric insecticides. 2. 1,10-Phenanthroline, a potent porphyric insecticide modulator",
abstract = "It is shown that in Trichoplusia ni, 1,10-phenanthroline, in addition to 2,2′-dipyridyl, exhibits potent contact porphyric insecticidal modulating properties. When sprayed with δ-aminolevulinic acid, 1,10-phenanthroline causes the larvae to accumulate massive amounts of protoporphyrin IX and lesser amounts of Zn-protoporphyrin IX in darkness and results in insect death in the light. In addition, ingestion of δ-aminolevulinic acid and 1,10-phenanthroline with the diet was extremely efficient in causing tetrapyrrole accumulation in darkness. This tetrapyrrole accumulation, in turn, was extremely efficient at producing insect death in the light, as evidenced by the low concentrations of δ-aminolevulinic acid (2 mM) and 1,10-phenanthroline (0.2 mM) that were sufficient to cause 100{\%} larval mortality. Several substituted 2,2′-dipyridyls and 1,10-phenanthrolines were also shown to act in concert with δ-aminolevulinic acid in causing larval death in the light.",
author = "Rebeiz, {Constantin A.} and Juvik, {John A} and Rebeiz, {Carole C.} and Bouton, {Carl E.} and Gut, {Larry J.}",
year = "1990",
month = "2",
doi = "10.1016/0048-3575(90)90011-P",
language = "English (US)",
volume = "36",
pages = "201--207",
journal = "Pesticide Biochemistry and Physiology",
issn = "0048-3575",
publisher = "Academic Press Inc.",
number = "2",

}

TY - JOUR

T1 - Porphyric insecticides. 2. 1,10-Phenanthroline, a potent porphyric insecticide modulator

AU - Rebeiz, Constantin A.

AU - Juvik, John A

AU - Rebeiz, Carole C.

AU - Bouton, Carl E.

AU - Gut, Larry J.

PY - 1990/2

Y1 - 1990/2

N2 - It is shown that in Trichoplusia ni, 1,10-phenanthroline, in addition to 2,2′-dipyridyl, exhibits potent contact porphyric insecticidal modulating properties. When sprayed with δ-aminolevulinic acid, 1,10-phenanthroline causes the larvae to accumulate massive amounts of protoporphyrin IX and lesser amounts of Zn-protoporphyrin IX in darkness and results in insect death in the light. In addition, ingestion of δ-aminolevulinic acid and 1,10-phenanthroline with the diet was extremely efficient in causing tetrapyrrole accumulation in darkness. This tetrapyrrole accumulation, in turn, was extremely efficient at producing insect death in the light, as evidenced by the low concentrations of δ-aminolevulinic acid (2 mM) and 1,10-phenanthroline (0.2 mM) that were sufficient to cause 100% larval mortality. Several substituted 2,2′-dipyridyls and 1,10-phenanthrolines were also shown to act in concert with δ-aminolevulinic acid in causing larval death in the light.

AB - It is shown that in Trichoplusia ni, 1,10-phenanthroline, in addition to 2,2′-dipyridyl, exhibits potent contact porphyric insecticidal modulating properties. When sprayed with δ-aminolevulinic acid, 1,10-phenanthroline causes the larvae to accumulate massive amounts of protoporphyrin IX and lesser amounts of Zn-protoporphyrin IX in darkness and results in insect death in the light. In addition, ingestion of δ-aminolevulinic acid and 1,10-phenanthroline with the diet was extremely efficient in causing tetrapyrrole accumulation in darkness. This tetrapyrrole accumulation, in turn, was extremely efficient at producing insect death in the light, as evidenced by the low concentrations of δ-aminolevulinic acid (2 mM) and 1,10-phenanthroline (0.2 mM) that were sufficient to cause 100% larval mortality. Several substituted 2,2′-dipyridyls and 1,10-phenanthrolines were also shown to act in concert with δ-aminolevulinic acid in causing larval death in the light.

UR - http://www.scopus.com/inward/record.url?scp=0025358274&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025358274&partnerID=8YFLogxK

U2 - 10.1016/0048-3575(90)90011-P

DO - 10.1016/0048-3575(90)90011-P

M3 - Article

AN - SCOPUS:0025358274

VL - 36

SP - 201

EP - 207

JO - Pesticide Biochemistry and Physiology

JF - Pesticide Biochemistry and Physiology

SN - 0048-3575

IS - 2

ER -