Abstract

We report a photonic crystal (PC) biosensor that incorporates a porous TiO2 film to boost sensitivity by enlarged surface area and enhanced interaction with the resonant electromagnetic fields. In the context of sensing small molecule interactions with proteins, the porous PC achieves 3.7x larger resonant wavelength shifts than an equivalent nonporous structure. Utilizing the porous PC as the wavelength selective element in an external cavity laser, the system provides narrow resonant linewidth via stimulated emission, and therefore establishes sub-picometer accuracy, representing a record high figure of merit for label free optical biosensors.

Original languageEnglish (US)
Title of host publicationIEEE Sensors, SENSORS 2016 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781479982875
DOIs
StatePublished - Jan 5 2017
Event15th IEEE Sensors Conference, SENSORS 2016 - Orlando, United States
Duration: Oct 30 2016Nov 2 2016

Publication series

NameProceedings of IEEE Sensors
ISSN (Print)1930-0395
ISSN (Electronic)2168-9229

Other

Other15th IEEE Sensors Conference, SENSORS 2016
CountryUnited States
CityOrlando
Period10/30/1611/2/16

Keywords

  • Photonic crystal
  • external cavity laser
  • small molecule detection

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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  • Cite this

    Huang, Q., Peh, J., Hergenrother, P. J., & Cunningham, B. T. (2017). Porous photonic crystal external cavity laser biosensor for drug screening. In IEEE Sensors, SENSORS 2016 - Proceedings [7808619] (Proceedings of IEEE Sensors). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICSENS.2016.7808619