Polysulfated Glycosaminoglycan as a Novel, Adjunctive Therapy for Pemphigus Foliaceus in Three Dogs

Andrew Simpson, Rod Rosychuck, Jennifer Schissler, Clarissa Souza

Research output: Contribution to journalArticlepeer-review

Abstract

Three dogs who were presented with cutaneous lesions and had histopathologic findings consistent with pemphigus foliaceus were treated with injectable polysulfated glycosaminoglycan as an adjunctive to systemic immune-modulatory therapy. These patients were not adequately controlled with oral glucocorticoids in conjunction with cyclosporine, azathioprine, and/or mycophenolate. Polysulfated glycosaminoglycan contributed to induction of remission and reduced glucocorticoid doses in all dogs.

Original languageEnglish (US)
Pages (from-to)318-322
Number of pages5
JournalJournal of the American Animal Hospital Association
Volume55
Issue number6
DOIs
StatePublished - Nov 2019
Externally publishedYes

ASJC Scopus subject areas

  • Small Animals

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