Polynucleotide barcoding

Matthew P Gordon; Paul R Selvin; Pui-Yan Kwok; Ming Xiao; Ting-Fung Chan

Polynucleotide barcoding

Matthew P Gordon (Inventor), Paul R Selvin (Inventor), Pui-Yan Kwok (Inventor), Ming Xiao (Inventor), Ting-Fung Chan (Inventor)

Research output: Patent

Abstract

A polynucleotide is barcoded using a method whereby an isolated, individual polynucleotide is immobilized on a solid phase and stretched, targets are labeled using target-specific hybridization probes, and an individual label of an unamplified probe at each of the labeled targets is optically detected. The order of the labels is determined to form a barcode representation of the polynucleotide wherein the targets and their relative positions are represented.

Original language	English (US)
U.S. patent number	7829278
Filing date	10/28/04
State	Published - Nov 9 2010

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title = "Polynucleotide barcoding",

abstract = "A polynucleotide is barcoded using a method whereby an isolated, individual polynucleotide is immobilized on a solid phase and stretched, targets are labeled using target-specific hybridization probes, and an individual label of an unamplified probe at each of the labeled targets is optically detected. The order of the labels is determined to form a barcode representation of the polynucleotide wherein the targets and their relative positions are represented.",

author = "Gordon, {Matthew P} and Selvin, {Paul R} and Pui-Yan Kwok and Ming Xiao and Ting-Fung Chan",

note = "This invention was made with US Government support under Grant Nos DBI-02-15869 and MCB-99-84841CAR awarded by the NSF; Grant Nos. PHS 5 R01-AR44420C and PHS 5 T32-GM08276 awarded by NIH; and Grant Nos. DEFG02-91ER45439 awarded by DOE. The Government has certain rights in this invention.; 7829278",

year = "2010",

month = nov,

day = "9",

language = "English (US)",

type = "Patent",

}

TY - PAT

T1 - Polynucleotide barcoding

AU - Gordon, Matthew P

AU - Selvin, Paul R

AU - Kwok, Pui-Yan

AU - Xiao, Ming

AU - Chan, Ting-Fung

N1 - This invention was made with US Government support under Grant Nos DBI-02-15869 and MCB-99-84841CAR awarded by the NSF; Grant Nos. PHS 5 R01-AR44420C and PHS 5 T32-GM08276 awarded by NIH; and Grant Nos. DEFG02-91ER45439 awarded by DOE. The Government has certain rights in this invention.

PY - 2010/11/9

Y1 - 2010/11/9

N2 - A polynucleotide is barcoded using a method whereby an isolated, individual polynucleotide is immobilized on a solid phase and stretched, targets are labeled using target-specific hybridization probes, and an individual label of an unamplified probe at each of the labeled targets is optically detected. The order of the labels is determined to form a barcode representation of the polynucleotide wherein the targets and their relative positions are represented.

AB - A polynucleotide is barcoded using a method whereby an isolated, individual polynucleotide is immobilized on a solid phase and stretched, targets are labeled using target-specific hybridization probes, and an individual label of an unamplified probe at each of the labeled targets is optically detected. The order of the labels is determined to form a barcode representation of the polynucleotide wherein the targets and their relative positions are represented.

M3 - Patent

M1 - 7829278

Y2 - 2004/10/28

ER -

Polynucleotide barcoding

Abstract

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