Polymer pen lithography (PPL)-induced site-specific click chemistry for the formation of functional glycan arrays

Shudan Bian, Jiajun He, Kevin B. Schesing, Adam B. Braunschweig

Research output: Contribution to journalArticlepeer-review

Abstract

Polymer pen lithography (PPL) can be combined with the Cu I-catalyzed azide-alkyne click reaction to create molecular arrays with control over orientation and sub-1 μm feature sizes over cm2 areas. The process has been applied to the deposition of carbohydrates to form functional glycochips.

Original languageEnglish (US)
Pages (from-to)2000-2005
Number of pages6
JournalSmall
Volume8
Issue number13
DOIs
StatePublished - Jul 9 2012
Externally publishedYes

Keywords

  • arrays
  • carbohydrates
  • click chemistry
  • dip-pen nanolithography
  • polymer pen lithography

ASJC Scopus subject areas

  • Biotechnology
  • General Chemistry
  • Biomaterials
  • General Materials Science
  • Engineering (miscellaneous)

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