Polyaspartamide vesicle induced by metallic nanoparticles

Jae Hyun Jeong, Chaenyung Cha, Amy Kaczmarowski, John Haan, Soonnam Oh, Hyunjoon Kong

Research output: Contribution to journalArticlepeer-review


Polymer vesicles are being extensively studied to emulate self-assembly in biological systems and also use them in a variety of biological and industrial applications. This study demonstrates a novel strategy to prepare polymer vesicles in a pure aqueous medium by driving the micelle-to-vesicle transition with metallic nanoparticles. We synthesized poly(2-amino-2-hydroxyethyl aspartamide) (PAHA) substituted with octadecyl chains, which could form micelle-like self-aggregates in the aqueous medium and chemically bind with platinum precursors. Then, in situ polymerization of Pt nanoparticles within the PAHA self-aggregates generated polymer vesicles that possess nanoparticles within bilayers, because of the increase of the hydrophilic mass ratio to total mass of PAHA, f (w). This new strategy to prepare polymer vesicles would greatly serve to facilitate the control of self-assembly and ultimately improve the functionality of a wide array of polymer vesicles.

Original languageEnglish (US)
Pages (from-to)2237-2242
Number of pages6
JournalSoft Matter
Issue number7
StatePublished - Feb 21 2012

ASJC Scopus subject areas

  • Chemistry(all)
  • Condensed Matter Physics


Dive into the research topics of 'Polyaspartamide vesicle induced by metallic nanoparticles'. Together they form a unique fingerprint.

Cite this