Plasmonic nanorainbow for label-free biomolecule sensing

Gang L. Liu, Erik H. Anderson, J. Alexander Liddle, Luke P. Lee

Research output: Contribution to journalConference article

Abstract

A gold nanowire array that we call nanorainbow SPR sensor array can be chemically functionalized and used to capture biomolecules. The localized plasmon resonance wavelength of the gold nanowires shifts on the biomolecule binding and reaction sites. The plasmon resonance shift of the gold nanorainbow is sensitive to the biomolecule immobilization in sub-nM concentration. As an application example, label-free oligonucleotide hybridizations are detected on the nanorainbow sensor in a multiplexed microfluidic chip.

Original languageEnglish (US)
Article number17
Pages (from-to)91-98
Number of pages8
JournalProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume5703
DOIs
StatePublished - Aug 16 2005
EventPlasmonics in Biology and Medicine II - San Jose, CA, United States
Duration: Jan 24 2005Jan 25 2005

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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